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运动领域中肠道微生物组分析的标准化。

Standardization of gut microbiome analysis in sports.

机构信息

Department of Biomedical Sciences, University of Padua, Padua, Italy; Human Inspired Technology Research Center HIT, University of Padua, Padua, Italy.

Department of Biomedical Sciences, University of Padua, Padua, Italy; Human Inspired Technology Research Center HIT, University of Padua, Padua, Italy.

出版信息

Cell Rep Med. 2024 Oct 15;5(10):101759. doi: 10.1016/j.xcrm.2024.101759. Epub 2024 Oct 4.

Abstract

The gut microbiome plays a significant role in physiological functions such as nutrient processing, vitamin production, inflammatory response, and immune modulation, which, in turn, are important contributors to athlete health and performance. To date, the interpretation, discussion, and visualization of microbiome results of athletes are challenging, due to a lack of standard parameters and reference data for collection and comparison. The purpose of this perspective piece is to provide researchers with an easy-to-understand framework for the collection, analysis, and data management related to the gut microbiome with a specific focus on athletic populations. In the absence of a consensus on microbiome research in the sports field, we hope that these considerations serve as foundational "best practice." Adherence to these standard operating procedures will accelerate the path toward improving the quality of data and ultimately our understanding of the influence of the gut microbiome in sport settings.

摘要

肠道微生物组在生理功能中发挥着重要作用,如营养处理、维生素生产、炎症反应和免疫调节,而这些功能反过来又是运动员健康和表现的重要贡献者。迄今为止,由于缺乏收集和比较的标准参数和参考数据,运动员的微生物组结果的解释、讨论和可视化具有挑战性。本文的目的是为研究人员提供一个易于理解的框架,用于收集、分析和管理与肠道微生物组相关的数据,特别是针对运动员群体。在运动领域的微生物组研究缺乏共识的情况下,我们希望这些考虑因素可以作为基础的“最佳实践”。遵守这些标准操作规程将加速提高数据质量的道路,并最终增进我们对肠道微生物组在运动环境中影响的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b33a/11514603/4a178e983330/gr1.jpg

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