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一项关于导引疗法改善老年人轻度认知障碍的效果和机制的系统评价。

A systematic review of the effect and mechanism of Daoyin therapy on improving mild cognitive impairment in older adults.

机构信息

Hunan University, Changsha City, Hunan Province, China.

Hunan University, Changsha City, Hunan Province, China.

出版信息

Ageing Res Rev. 2024 Nov;101:102526. doi: 10.1016/j.arr.2024.102526. Epub 2024 Oct 4.

Abstract

BACKGROUND

Age-related cognitive decline is a pervasive problem in the aging population. Daoyin therapy is a mind-body movement characteristic of traditional Chinese medicine (TCM). Increasing evidence has reported its usefulness in improving cognitive function among different populations. However, there is no systematic review to assess the effect and mechanism of Daoyin therapy on mild cognitive dysfunction (MCI) in older adults.

OBJECTIVE

To systematically review the evidence on the effect and mechanism of Daoyin therapy on MCI in older adults.

RESULTS

Taichi, Baduanjin, and Yijinjing can improve cognitive function. Qigong and Wuqinxi can enhance the physical and cognitive functions related to balance, muscle strength, physical endurance, postural control, and flexibility. Taichi, Baduanjin, and Wuqinxi can improve the cognitive function of older adults and alleviate the symptoms associated with MCI through multiple mechanisms. The underlying mechanisms include activating the expression of signals and changing their connections in different brain regions, increasing brain capacity, and regulating brain-derived neurotropic and inflammatory factors.

CONCLUSION

In summary, the existing evidence from RCTs suggests that traditional Daoyin therapy, such as Taichi, Baduanjin, and Wuqinxi, is a promising strategy that can improve cognitive function and delay the onset of dementia in older adults with MCI by altering structural and neural activities and modulating other factors.

摘要

背景

与年龄相关的认知能力下降是老龄化人口中普遍存在的问题。导引术是一种具有中医特色的身心运动。越来越多的证据表明,它在改善不同人群的认知功能方面是有效的。然而,目前尚无系统评价来评估导引术对老年人轻度认知功能障碍(MCI)的疗效和作用机制。

目的

系统评价导引术对老年人 MCI 的疗效和作用机制。

结果

太极拳、八段锦和易筋经可以改善认知功能。气功和五禽戏可以增强与平衡、肌肉力量、身体耐力、姿势控制和柔韧性相关的身体和认知功能。太极拳、八段锦和五禽戏可以通过多种机制改善老年人的认知功能,缓解与 MCI 相关的症状。其潜在机制包括激活不同脑区信号的表达及其连接的改变、增加脑容量以及调节脑源性神经营养因子和炎症因子。

结论

综上所述,现有的 RCT 证据表明,传统的导引术,如太极拳、八段锦和五禽戏,是一种有前途的策略,可以通过改变结构和神经活动以及调节其他因素,改善认知功能,延缓 MCI 老年人痴呆的发生。

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