Li Xiaoyi, Shao Zhen, Li Zhi, Wei Xiupan, Zong Lijuan, Wang Pei, Zhou Ting, Wang Hongxing
Department of Rehabilitation Medicine, Zhongda Hospital Southeast University, School of Medicine, Southeast University, Nanjing, China.
Department of Rehabilitation Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Front Neurol. 2024 Sep 20;15:1466252. doi: 10.3389/fneur.2024.1466252. eCollection 2024.
This study investigates the correlation between neuroelectrop-hysiological assessments such as motor unit number estimation (MUNE) and F-waves with upper extremity motor function and one-year prognosis in stroke patients.
Neuroelectrophysiological assessments of the abductor pollicis brevis muscle, including MUNE and F-waves, were conducted. Upper extremity motor function was evaluated using the Fugl-Meyer Assessment of Upper Extremity (FMA-UE) and the Modified Ashworth Scale (MAS). Pearson correlation and multiple linear regression analyses were performed to explore the relationship between upper extremity motor function and variables such as MUNE and F-waves. ROC curve analysis assessed the predictive ability of MUNE and F-waves for upper extremity motor function, and binary logistic regression analysis examined factors related to motor function improvement 1 year post-discharge.
A total of 130 patients were ultimately included. Significant differences in MUNE and occupancy rate of non-repeater F-waves (non-ORF) were found between hemiplegic and unaffected sides ( < 0.001), with a significant difference in F-wave mean latency ( < 0.05). Pearson correlation analysis showed a positive correlation between FMA-UE at admission and hemiplegic side's MUNE and non-ORF ( < 0.001). Multiple linear regression indicated that hemiplegic side's MUNE ( = 0.88, < 0.001) and non-ORF ( = 0.275, = 0.005) influenced FMA-UE. ROC analysis demonstrated higher predictive ability for hemiplegic side's MUNE (AUC = 0.696, < 0.001) than non-ORF (AUC = 0.622, = 0.018). Binary logistic regression showed that hemiplegic side's MUNE was associated with FMA-UE improvement 1 year post-discharge.
MUNE and F-waves are correlated with upper extremity motor function in patients, reflecting their motor function status. These indicators have good predictive value for motor function and are associated with the prognosis of upper extremity motor function to a certain extent.
本研究调查运动单位数量估计（MUNE）和F波等神经电生理评估与脑卒中患者上肢运动功能及一年预后之间的相关性。
对拇短展肌进行包括MUNE和F波在内的神经电生理评估。使用上肢Fugl-Meyer评估量表（FMA-UE）和改良Ashworth量表（MAS）评估上肢运动功能。进行Pearson相关性分析和多元线性回归分析，以探讨上肢运动功能与MUNE和F波等变量之间的关系。ROC曲线分析评估MUNE和F波对上肢运动功能的预测能力，二元逻辑回归分析检查与出院后1年运动功能改善相关的因素。
最终纳入130例患者。偏瘫侧与非偏瘫侧在MUNE和非重复F波占有率（non-ORF）方面存在显著差异（<0.001），F波平均潜伏期也存在显著差异（<0.05）。Pearson相关性分析显示入院时FMA-UE与偏瘫侧的MUNE和non-ORF呈正相关（<0.001）。多元线性回归表明，偏瘫侧的MUNE（=0.88，<0.001）和non-ORF（=0.275，=0.005）影响FMA-UE。ROC分析表明，偏瘫侧的MUNE（AUC=0.696，<0.001）比non-ORF（AUC=0.622，=0.018）具有更高的预测能力。二元逻辑回归显示，偏瘫侧的MUNE与出院后1年FMA-UE的改善相关。
MUNE和F波与患者的上肢运动功能相关，反映了他们的运动功能状态。这些指标对运动功能具有良好的预测价值，并在一定程度上与上肢运动功能的预后相关。
