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全球和国家归因于 PM2.5 空气污染的 2 型糖尿病的负担:来自 1990 年至 2019 年 GBD 研究的分析。

Global and national burden of type 2 diabetes mellitus attributable to PM2.5 air pollution: An analysis of the GBD study from 1990 to 2019.

机构信息

Hawken High School, Ohio, USA.

Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

出版信息

Physiol Rep. 2024 Oct;12(19):e70074. doi: 10.14814/phy2.70074.

Abstract

Epidemiological studies have established a link between air pollution and an elevated risk of type 2 diabetes mellitus (T2DM). This study aims to measure the impact of T2DM related to fine particulate matter (PM2.5) pollution by examining death rates and disability-adjusted life years (DALYs) from 1990 to 2019 in the United States of America. Using data from the Global Burden of Disease (GBD) database, we examined death and DALY rates per 100,000 populations in T2DM patients, specifically focusing on ambient particulate matter pollution (APMP) and household air pollution (HAP). We assessed average annual percentage change (AAPC) across various age and gender groups, states, and socio-demographic index (SDI) categories. Our findings reveal a significant decline in death rates and DALYs in the United States of America over the last 30 years, with more pronounced decreases among females and older adults. Despite national progress, state-level variations indicate complex interactions between environmental regulations, healthcare access, and socio-economic factors. Some states, such as Oregon, Idaho, and Alaska, exhibited increased AAPC. Our study emphasizes the need for targeted policies and interventions to reduce PM exposure and further address regional disparities, ensuring continued improvement in public health outcomes.

摘要

流行病学研究已经确立了空气污染与 2 型糖尿病(T2DM)风险升高之间的联系。本研究旨在通过检查 1990 年至 2019 年美国因细颗粒物(PM2.5)污染导致的死亡率和伤残调整生命年(DALY),来衡量 T2DM 相关的影响。我们使用全球疾病负担(GBD)数据库的数据,研究了 T2DM 患者每 10 万人的死亡和 DALY 率,特别关注环境细颗粒物污染(APMP)和家庭空气污染(HAP)。我们评估了不同年龄和性别组、各州以及社会人口指数(SDI)类别中每年的平均百分比变化(AAPC)。我们的研究结果表明,在过去的 30 年里,美国的死亡率和 DALY 显著下降,女性和老年人的下降更为明显。尽管取得了国家进展,但州一级的差异表明环境法规、医疗保健获取和社会经济因素之间存在复杂的相互作用。一些州,如俄勒冈州、爱达荷州和阿拉斯加,表现出 AAPC 的增加。我们的研究强调需要采取有针对性的政策和干预措施来减少 PM 暴露,并进一步解决地区差异,以确保公共卫生结果的持续改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d45f/11458325/0d8e94b369ad/PHY2-12-e70074-g001.jpg

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