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喉组织胞浆菌病罕见病例:诊断难题

Rare Case of Laryngeal Histoplasmosis: A Diagnostic Challenge.

作者信息

Vyas Pratibha, Kataria Tanmaya, Soni Nikhil, Nimawat Atul

机构信息

Department of Otorhinolaryngology, Mahatma Gandhi Medical college, Jaipur, Rajasthan, 302033 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4788-4793. doi: 10.1007/s12070-024-04849-8. Epub 2024 Jul 6.

Abstract

Granulomatous lesions, though rare, can affect diverse body regions, including the larynx, presenting diagnostic challenges. In India, where malignancy and tuberculosis prevail, fungal infections are often overlooked. We present a case of 34 year old male with complaint of change in voice which was approached as malignancy but later turned out to be histoplasmosis on histopathology. Diagnostic challenges arise due to symptoms overlapping with other conditions. Our case underscores the importance of considering fungal etiologies in endemic regions, especially when symptoms persist despite treatment.

摘要

肉芽肿性病变虽然罕见,但可累及包括喉部在内的不同身体部位,带来诊断挑战。在恶性肿瘤和结核病高发的印度,真菌感染常常被忽视。我们报告一例34岁男性病例,患者因声音改变就诊,最初被当作恶性肿瘤处理,但组织病理学检查后来证实为组织胞浆菌病。由于症状与其他疾病重叠,导致诊断困难。我们的病例强调了在地方病流行地区考虑真菌病因的重要性,尤其是在治疗后症状仍持续存在的情况下。

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Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):4899-4901. doi: 10.1007/s12070-021-02405-2. Epub 2021 Jan 31.
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