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一例与凝血因子Ⅻ活性降低相关的自发性双侧硬膜外血肿:病例报告及文献复习

A case of spontaneous bilateral epidural hematoma associated with decreased coagulation factor XII activity: case report and literature review.

作者信息

Tang Zhuxiao, Wang Ming, Xiong Tao, Liu Weixian, Sun Hu, Ma Jiangchun

机构信息

Brain Center, Zhejiang Hospital, Hangzhou, Zhejiang, China.

出版信息

Front Neurol. 2024 Sep 23;15:1460073. doi: 10.3389/fneur.2024.1460073. eCollection 2024.

Abstract

Epidural hematoma typically manifests following craniocerebral trauma, stemming from injury to the meningeal artery or venous system, predominantly on one side. Instances of spontaneous epidural hematoma are uncommon, with occurrences of spontaneous bilateral epidural hematoma being exceedingly rare. Sickle cell disease, adjacent paranasal sinusitis, and tumor metastases are the most prevalent causes of spontaneous epidural hematoma. This case study presents an individual with abdominal liposarcoma exhibiting reduced coagulation factor XII activity, who experienced sudden unconsciousness due to spontaneous acute bilateral epidural hematoma, and subsequently achieved a favorable outcome following surgical intervention.

摘要

硬膜外血肿通常在颅脑外伤后出现,源于脑膜动脉或静脉系统损伤,主要发生在一侧。自发性硬膜外血肿的情况并不常见,自发性双侧硬膜外血肿的发生极为罕见。镰状细胞病、邻近鼻窦炎症和肿瘤转移是自发性硬膜外血肿最常见的原因。本病例研究介绍了一名患有腹部脂肪肉瘤且凝血因子XII活性降低的患者,该患者因自发性急性双侧硬膜外血肿突然昏迷,随后经手术干预取得了良好效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a90/11456527/6a9fc8597b21/fneur-15-1460073-g001.jpg

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