Sahota Richa, Gambhir Ramandeep, Anand Samir, Dixit Avani
Department of Oral Pathology, Rayat and Bahra Dental College and Hospital, Mohali.
Department of Public Health Dentistry, Gian Sagar Dental College and Hospital, Rajpura.
Ethiop J Health Sci. 2017 Jan;27(1):85-90. doi: 10.4314/ejhs.v27i1.11.
Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes.
We report a case of rhinocerebral mucormycosis in a 75 year-old diabetic patient with emphasise on diagnosis, treatment and survival options of patient from this potentially fatal fungal infection. Extra oral examination revealed mild non-tender swelling on the face, unable to see from left eye, impaired sense of smell, difficulty in speech and nasal stuffiness. Intra-oral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla.
Timely diagnosis is critical to survival and minimization of morbidity. Institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome.
毛霉病是一种进展迅速且致命的真菌感染形式，累及头颈部的鼻腔和鼻窦。毛霉病对糖尿病控制不佳或有其他易患全身性疾病的患者仍然构成威胁。它表现为鼻脑型、肺型、胃肠型、皮肤型或播散型。基础疾病会影响临床表现，常常延误诊断，导致不良后果。
我们报告一例75岁糖尿病患者的鼻脑型毛霉病病例，重点关注该潜在致命真菌感染患者的诊断、治疗及生存选择。口腔外检查发现面部轻度无压痛肿胀，左眼失明，嗅觉减退，言语困难和鼻塞。口腔内检查显示上颌左侧前庭区从尖牙至结节区域的黏膜及下方骨质坏死。
及时诊断对于生存及降低发病率至关重要。实施手术和药物治疗对于提高良好预后的可能性至关重要。
