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基于支持向量机和粒子群优化算法的急性淋巴细胞白血病混合检测模型(SVM-PSO)。

A hybrid detection model for acute lymphocytic leukemia using support vector machine and particle swarm optimization (SVM-PSO).

机构信息

Department of Software Engineering, College of Computer and Information Sciences, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.

出版信息

Sci Rep. 2024 Oct 8;14(1):23483. doi: 10.1038/s41598-024-74889-1.

DOI:10.1038/s41598-024-74889-1
PMID:39379598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11461623/
Abstract

Leukemia, a hematological disease affecting the bone marrow and white blood cells (WBCs), ranks among the top ten causes of mortality worldwide. Delays in decision-making often hinder the timely application of suitable medical treatments. Acute lymphoblastic leukemia (ALL) is one of the primary forms, constituting approximately 25% of childhood cancer cases. However, automated ALL diagnosis is challenging. Recently, machine learning (ML) has emerged as an important tool for building detection models. In this study, we present a hybrid detection model that improves the accuracy of the detection process by combining support vector machine (SVM) and particle swarm optimization (PSO) approaches to automatically identify ALL. We use SVM to represent a two-dimensional image and complete the classification process. PSO is employed to enhance the performance of the SVM model, reducing error rates and enhancing result accuracy. The input images are obtained from two public datasets (ALL-IDB1 and ALL-IDB2), and public online datasets are utilized for training and testing the proposed model. The results indicate that our hybrid SVM-PSO model has high accuracy, outperforming stand-alone algorithms and demonstrating superior performance, an enhanced confusion matrix, and a higher detection rate. This advancement holds promise for enhancing the quality of technical software in the medical field using machine learning.

摘要

白血病是一种影响骨髓和白细胞(WBC)的血液疾病,是全球十大死亡原因之一。决策延误常常阻碍了合适医疗治疗的及时应用。急性淋巴细胞白血病(ALL)是主要形式之一,占儿童癌症病例的约 25%。然而,自动 ALL 诊断具有挑战性。最近,机器学习(ML)已成为构建检测模型的重要工具。在这项研究中,我们提出了一种混合检测模型,通过结合支持向量机(SVM)和粒子群优化(PSO)方法来自动识别 ALL,从而提高检测过程的准确性。我们使用 SVM 表示二维图像并完成分类过程。PSO 用于增强 SVM 模型的性能,降低错误率并提高结果准确性。输入图像来自两个公共数据集(ALL-IDB1 和 ALL-IDB2),并使用公共在线数据集对提出的模型进行训练和测试。结果表明,我们的混合 SVM-PSO 模型具有很高的准确性,优于独立算法,并表现出卓越的性能、增强的混淆矩阵和更高的检测率。这一进展有望通过机器学习提高医疗领域技术软件的质量。

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