新型β-内酰胺类抗生素对124株革兰氏阴性杆菌的体外活性。
The in vitro activity of the newer beta-lactam antibiotics against 124 strains of gram-negative bacilli.
作者信息
Dixson S, Andrew J H
出版信息
Pathology. 1985 Oct;17(4):636-9. doi: 10.3109/00313028509084767.
PMID:3938006
Abstract
The MIC values of 99 isolates of Enterobacteriaceae to 11 of the newer beta-lactam antibiotics, and 25 isolates of Pseudomonas aeruginosa to 9 of these drugs were compared with representatives of the established beta-lactam antibiotics and gentamicin. The MIC values for the newer agents were significantly lower in comparison with the older reference compounds. The potential clinical use of these newer antibiotics is discussed.
摘要
对99株肠杆菌科细菌针对11种新型β-内酰胺类抗生素的最低抑菌浓度（MIC）值，以及25株铜绿假单胞菌针对其中9种药物的MIC值，与已确立的β-内酰胺类抗生素及庆大霉素的代表药物进行了比较。与较老的对照化合物相比，新型药物的MIC值显著更低。讨论了这些新型抗生素的潜在临床用途。
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