依诺沙星、替卡西林加克拉维酸、氨曲南、哌拉西林和亚胺培南的体外活性及其与常用抗菌药物的比较。
In vitro activities of enoxacin, ticarcillin plus clavulanic acid, aztreonam, piperacillin, and imipenem and comparison with commonly used antimicrobial agents.
作者信息
Henry D, Skidmore A G, Ngui-Yen J, Smith A, Smith J A
出版信息
Antimicrob Agents Chemother. 1985 Aug;28(2):259-64. doi: 10.1128/AAC.28.2.259.
Abstract
A total of 745 gram-negative and 313 gram-positive clinical isolates were tested against enoxacin, ticarcillin plus clavulanic acid, aztreonam, imipenem, and piperacillin and compared with commonly used antimicrobial agents. Ticarcillin plus clavulanic acid, imipenem, and piperacillin were active against Pseudomonas aeruginosa and Acinetobacter spp. and most Pseudomonas spp. Aztreonam was active against members of the family Enterobacteriaceae but was less effective against the nonfermenters. Enoxacin was active against the Enterobacteriaceae, P. aeruginosa, the staphylococci, and most Acinetobacter spp. but was less active against Pseudomonas spp. and streptococci. Imipenem was very active against all gram-positive and -negative organisms tested except for Pseudomonas maltophilia.
摘要
共对745株革兰氏阴性和313株革兰氏阳性临床分离菌株进行了依诺沙星、替卡西林加克拉维酸、氨曲南、亚胺培南和哌拉西林的测试，并与常用抗菌药物进行了比较。替卡西林加克拉维酸、亚胺培南和哌拉西林对铜绿假单胞菌、不动杆菌属以及大多数假单胞菌属具有活性。氨曲南对肠杆菌科成员有活性，但对非发酵菌的效果较差。依诺沙星对肠杆菌科、铜绿假单胞菌、葡萄球菌以及大多数不动杆菌属有活性，但对假单胞菌属和链球菌的活性较低。亚胺培南对除嗜麦芽窄食单胞菌外的所有测试革兰氏阳性和阴性菌都非常有活性。
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