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塔拉瓦纳综合征与后部可逆性脑病综合征:屏气潜水员神经意外的微泡假说

Taravana syndrome and posterior reversible encephalopathy syndrome: a microbubble hypothesis for neurological accidents in breath-hold divers.

作者信息

Druelle Arnaud, Castagna Olivier, Roffi Romain, Louge Pierre, Faivre Anthony, Blatteau Jean-Eric

机构信息

Service de Médecine Hyperbare et d'Expertise Plongée (SMHEP), Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.

Equipe de Recherche Subaquatique et Hyperbare, Institut de Recherche Biomédicale des Armées, Toulon, France.

出版信息

Front Physiol. 2024 Sep 24;15:1478650. doi: 10.3389/fphys.2024.1478650. eCollection 2024.

Abstract

Breath-hold diving is a challenging activity that can lead to serious and dangerous complications, such as the "Taravana" syndrome. This syndrome is characterized by the onset of neurological symptoms after deep or repeated dives. The main clinical manifestations are cerebral, including stroke and cognitive impairment. The pathophysiology of Taravana syndrome is still widely debated, but the most accepted theory is that it is a specific form of decompression sickness. We have reviewed the main theories explaining the onset of Taravana syndrome and, through the description of a particularly illustrative case of a freediver using an underwater scooter, we have formulated a hypothesis according to which micro-bubbles formed directly in cerebral structures would be at the origin of this syndrome. MRI showed diffuse encephalopathy with vasogenic edema. Analysis of the radiological sequences did not suggest an ischemic or embolic mechanism. This finding is likely to be associated with the diagnosis of posterior reversible encephalopathy syndrome. The rapid ascent speeds associated with underwater scooter use could potentially result in the formation of nitrogen micro-bubbles in the capillaries of brain tissue. The emergence of scooters in freediving can be a hazard because of their ability to facilitate very rapid ascents. It is therefore essential to take preventive measures to ensure the safety of users of these devices.

摘要

屏气潜水是一项具有挑战性的活动,可能会导致严重且危险的并发症,如“塔拉瓦纳”综合征。该综合征的特征是在深度潜水或反复潜水后出现神经症状。主要临床表现为脑部症状,包括中风和认知障碍。塔拉瓦纳综合征的病理生理学仍存在广泛争议,但最被认可的理论是它是减压病的一种特殊形式。我们回顾了解释塔拉瓦纳综合征发病的主要理论,并通过描述一名使用水下踏板车的自由潜水者的典型案例,提出了一个假设,即直接在脑结构中形成的微气泡是该综合征的根源。磁共振成像显示弥漫性脑病伴血管源性水肿。对放射学序列的分析未提示缺血或栓塞机制。这一发现可能与后部可逆性脑病综合征的诊断有关。与使用水下踏板车相关的快速上升速度可能会导致在脑组织毛细血管中形成氮微气泡。自由潜水中水下踏板车的出现可能是一种危险,因为它们能够促使潜水者非常快速地上升。因此,采取预防措施以确保这些设备使用者的安全至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/779b/11458415/a2249ceb0a27/fphys-15-1478650-g001.jpg

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