用于混合运动/感觉神经重建的自体神经移植物与同种异体移植物的比较
Nerve Autografts Versus Allografts for Mixed Motor/Sensory Nerve Reconstruction.
作者信息
Saffari Sara, Shin Alexander Y, Pulos Nicholas
机构信息
Division of Hand and Microvascular Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Department of Plastic Surgery, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands.
出版信息
J Hand Surg Glob Online. 2024 Apr 20;6(5):694-699. doi: 10.1016/j.jhsg.2024.01.025. eCollection 2024 Sep.
Abstract
Reconstruction of peripheral mixed motor/sensory nerves using autografts has remained the gold standard. Inconsistent and nonphysiologic results across nerve allograft studies, including successful and failed motor reinnervation, have limited the current clinical application of nerve allografts to noncritical small-diameter sensory nerve defects less than 3 cm. This scoping review aimed to compare outcomes in both basic science and clinical applications of autograft and allograft nerve reconstruction for mixed motor/sensory nerves.
摘要
使用自体移植物重建周围混合运动/感觉神经仍然是金标准。在包括成功和失败的运动再支配在内的同种异体神经移植研究中，结果不一致且不符合生理情况，这限制了目前同种异体神经移植在小于3厘米的非关键小直径感觉神经缺损中的临床应用。本综述旨在比较自体移植和同种异体移植重建混合运动/感觉神经在基础科学和临床应用方面的结果。
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