Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Department of Pharmacy, Longgang Distract People's Hospital of Shenzhen & The Third Affiliated Hospital (Provisional) of Chinese University of Hong Kong (Shenzhen), Shenzhen, 518172, China.
BMC Med Inform Decis Mak. 2024 Oct 9;24(1):294. doi: 10.1186/s12911-024-02701-1.
In recent years, mobile medical technology has made great progress in chronic disease management, but its application in patients with atrial fibrillation (AF) still needs to be clarified.
This study aims to determine whether the newly developed smartphone app for patients with AF (Alfalfa App) can improve anticoagulation knowledge, drug treatment compliance, and satisfaction of AF patients.
Alfalfa App integrates the functions of patient education, remote consultation, and medication reminder through a simple user interface. From June 2020 to December 2020, patients with AF were recruited in five large tertiary hospitals in China. Patients were randomly divided into the Alfalfa App or routine nursing groups. Patients' knowledge, medication adherence, and satisfaction with anticoagulation were assessed using validated questionnaires at baseline, 1 month, and 3 months.
In this randomized controlled trial, 113 patients with AF were included, 57 patients were randomly assigned to the Alfalfa App group, and 56 patients were randomly assigned to the routine nursing group. Forty-eight patients in the Alfalfa App group completed a three-month follow-up, and 48 patients in the routine nursing group completed a three-month follow-up. Basic demographic data were comparable between the two groups. The average age of AF patients was 61.65 ± 11.01 years old, and 61.5% of them were male. With time (baseline to 3 months), the knowledge scores of the Alfalfa App group (P<.001) and the routine nursing group (P = .002) were significantly improved, the compliance scores of the routine nursing group(P<.001) and Alfalfa App group(P<.001) significantly improved. Compared with the routine nursing group, patients' knowledge level and medication compliance using the Alfalfa App at 1 month and 3 months were significantly higher (all P < .05). There were significant differences in knowledge and compliance scores between the two groups with time (all P < .05). The satisfaction degree of drug treatment in the Alfalfa App group was significantly better than that in the routine nursing group (all P < .05).
Alfalfa App significantly improved the anticoagulation knowledge, drug treatment compliance, and satisfaction of AF patients. In oral anticoagulation management for AF patients, mobile medical technology that integrates the functions of patient education, remote consultation, and medication reminder may be helpful.
Registration number, ChiCTR1900024455. Registered on July 12, 2019.
近年来，移动医疗技术在慢性病管理方面取得了长足的进步，但在心房颤动（AF）患者中的应用仍需明确。
本研究旨在确定新开发的用于 AF 患者的智能手机应用程序（Alfalfa App）是否可以提高 AF 患者的抗凝知识、药物治疗依从性和满意度。
Alfalfa App 通过简单的用户界面集成了患者教育、远程咨询和用药提醒功能。2020 年 6 月至 2020 年 12 月，在中国五家大型三级医院招募 AF 患者。患者被随机分为 Alfalfa App 组或常规护理组。在基线、1 个月和 3 个月时使用经过验证的问卷评估患者的知识、药物依从性和抗凝满意度。
在这项随机对照试验中，纳入了 113 例 AF 患者，其中 57 例患者被随机分配至 Alfalfa App 组，56 例患者被随机分配至常规护理组。Alfalfa App 组有 48 例患者完成了三个月的随访，常规护理组有 48 例患者完成了三个月的随访。两组患者的基本人口统计学数据相似。AF 患者的平均年龄为 61.65±11.01 岁，其中 61.5%为男性。随着时间的推移（基线至 3 个月），Alfalfa App 组（P<.001）和常规护理组（P=0.002）的知识评分均显著提高，常规护理组（P<.001）和 Alfalfa App 组（P<.001）的依从评分均显著提高。与常规护理组相比，患者在使用 Alfalfa App 1 个月和 3 个月时的知识水平和用药依从性均显著更高（均 P<.05）。两组的知识和依从评分均随时间变化而有显著差异（均 P<.05）。Alfalfa App 组的药物治疗满意度明显优于常规护理组（均 P<.05）。
Alfalfa App 显著提高了 AF 患者的抗凝知识、药物治疗依从性和满意度。在口服抗凝治疗 AF 患者中，整合患者教育、远程咨询和用药提醒功能的移动医疗技术可能会有所帮助。
注册号，ChiCTR1900024455。注册于 2019 年 7 月 12 日。
