Zhang Xiao-Bo, Gao Zilin, Yao Xin, Xu Zheng-Wei, Hao Ding-Jun
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.
Int Orthop. 2025 Jan;49(1):195-202. doi: 10.1007/s00264-024-06328-9. Epub 2024 Oct 10.
To compare the clinical efficacy of 3D-printed artificial discs with that of ACDF for treating cervical spondylosis.
This was a retrospective analysis of 73 patients with single-level cervical spondylosis who met the inclusion criteria between January 2020 and December 2022 at XX Hospital. The patients were divided: 38 patients in the ACDF group and 35 patients in the CADR group. Patient general information, including operation time and intraoperative blood loss, was collected. The clinical effect of the combination therapy was evaluated by the VAS, JOA, and NDI. The radiological effect was evaluated using the ROM test. Ethics No. 201,606,009.
The average follow-up times in the ACDF and CADR groups were 28.24 ± 4.65 and 29.11 ± 5.06 months, respectively (P = 0.443). Clinical symptoms (evaluated by VAS, NDI, and JOA) are significantly improved in both the ACDF and CADR groups with similar efficacy. The preoperative ROM of the ACDF group was 40.03 ± 8.79, while that of the CADR group was 42.11 ± 7.98 (P = 0.293). However, the postoperative ROM in the ACDF group was 35.29 ± 7.23, which was lower than that in the CADR group (40.43 ± 6.98) (P = 0.003). Furthermore, only one patient in the ACDF group experienced mild dysphagia after surgery, and the patient recovered within three days. ASD occurred in nine patients in the ACDF group and in two patients in the CADR group (Χ²=4.597, P = 0.032).
Compared with ACDF, 3D-printed artificial discs for treating single-level cervical spondylosis have proven to be clinically effective; it associated with less blood loss and a lower incidence of ASD, and maintain a better cervical ROM.
比较3D打印人工椎间盘与前路颈椎间盘切除融合术（ACDF）治疗颈椎病的临床疗效。
对XX医院2020年1月至2022年12月期间符合纳入标准的73例单节段颈椎病患者进行回顾性分析。患者分为：ACDF组38例，CADR组35例。收集患者的一般信息，包括手术时间和术中出血量。采用视觉模拟评分法（VAS）、日本骨科学会（JOA）评分和颈部功能障碍指数（NDI）评估联合治疗的临床效果。采用活动度（ROM）测试评估影像学效果。伦理编号：201,606,009。
ACDF组和CADR组的平均随访时间分别为28.24±4.65个月和29.11±5.06个月（P = 0.443）。ACDF组和CADR组的临床症状（通过VAS、NDI和JOA评估）均有显著改善，疗效相似。ACDF组术前ROM为40.03±8.79，而CADR组为42.11±7.98（P = 0.293）。然而，ACDF组术后ROM为35.29±7.23，低于CADR组（40.43±6.98）（P = 0.003）。此外，ACDF组仅1例患者术后出现轻度吞咽困难，3天内恢复。ACDF组9例患者发生相邻节段退变（ASD），CADR组2例患者发生（Χ²=4.597，P = 0.032）。
与ACDF相比，3D打印人工椎间盘治疗单节段颈椎病已被证明具有临床疗效；它与较少的出血量和较低的ASD发生率相关，并能保持更好的颈椎活动度。
