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在脱水风险期间的药物管理:一项针对肾功能受损的老年患者和非正规照护者的定性研究。

Medication management during risk of dehydration: A qualitative study among elderly patients with impaired renal function and informal caregivers.

机构信息

Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

Eur J Gen Pract. 2024 Dec;30(1):2413097. doi: 10.1080/13814788.2024.2413097. Epub 2024 Oct 11.

Abstract

BACKGROUND

Patients with impaired renal function are at an increased risk of dehydration due to vomiting, diarrhoea or fever (so-called sick days). Temporary medication adjustment during sick days is necessary and current initiatives and information materials for patients are available. However, the knowledge, experiences and information needs of patients and informal caregivers about sick day guidance are unknown.

AIM

To gain insight into the understanding of safe medication use during periods of dehydration risk in elderly patients with impaired renal function and their informal caregivers.

DESIGN AND SETTING

Qualitative interview study with patients with impaired renal function and unrelated informal caregivers from three community pharmacies in the Netherlands.

METHOD

The interviews were conducted by telephone or live by two researchers in November 2020-September 2021 and audiotaped and transcribed verbatim. The coding of transcripts was performed deductively and inductively in Nvivo 12, a thematic analysis was applied.

RESULTS

In total 12 patients and 11 unrelated informal caregivers were included. Three main themes were derived from the interview guide and subthemes emerged from the transcripts. The included patients and informal caregivers had limited knowledge about medication management during sick days. In contrast to patients, informal caregivers seemed interested in a medication management protocol for sick days.

CONCLUSION

Patients with impaired renal function and informal caregivers have little knowledge about and experience with dehydration and safe use of medication during sick days. General practitioners and pharmacists should involve the care network, including informal caregivers, when implementing sick day guidance.

摘要

背景

肾功能受损的患者由于呕吐、腹泻或发热(所谓的“生病日”)而面临脱水风险增加的情况。在生病日期间,需要对药物进行临时调整,并且目前有针对患者的举措和信息材料。然而,患者及其非专业护理人员对生病日指导的知识、经验和信息需求尚不清楚。

目的

深入了解肾功能受损的老年患者及其非专业护理人员在脱水风险期间安全使用药物的理解。

设计和设置

这是一项在荷兰的三家社区药店进行的具有肾功能受损的患者和无关的非专业护理人员的定性访谈研究。

方法

访谈于 2020 年 11 月至 2021 年 9 月间通过电话或现场进行,由两名研究人员进行,并进行了录音和逐字转录。使用 Nvivo 12 软件对转录本进行了演绎和归纳式编码,并应用了主题分析。

结果

共纳入了 12 名患者和 11 名无关的非专业护理人员。从访谈指南中得出了三个主要主题,并从转录本中出现了子主题。纳入的患者和非专业护理人员对生病日期间的药物管理知之甚少。与患者不同,非专业护理人员似乎对生病日的药物管理方案感兴趣。

结论

肾功能受损的患者及其非专业护理人员对脱水和生病日安全用药知之甚少,经验有限。全科医生和药剂师在实施生病日指导时应让护理网络(包括非专业护理人员)参与进来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3d1/11486018/4ed7a393351e/IGEN_A_2413097_F0001_C.jpg

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