放射治疗通讯：一只犬经组织学确诊的多发性少突胶质细胞瘤播散性转移灶的立体定向放射再治疗

Rancilio Nicholas J, Murakami Keiko, Harm Tyler, Christensen Neil

Department of Veterinary Clinical Sciences and Department of Pathology Iowa State, University College of Veterinary Medicine, Ames, Iowa, USA.

Department of Surgical Sciences, The University of Wisconsin, School of Veterinary Medicine, Madison, Wisconsin, USA.

Vet Radiol Ultrasound. 2025 Jan;66(1):e13454. doi: 10.1111/vru.13454. Epub 2024 Oct 12.

A 10-year-old female spayed boxer was treated with stereotactic radiotherapy (SRT) for a suspected glioma in the left piriform lobe. The intra-axial lesion was T2 hyperintense, T2 FLAIR hyperintense, T1 hypointense, and did not uptake contrast. Imaging was performed with an MRI every 3 months, and at the 6-month recheck, new lesions in the left hippocampus and right piriform lobe were evident without clinically apparent neurological progression. A second course of SRT was prescribed for the new lesions. Euthanasia was elected 14 months after the first course of SRT, and necropsy confirmed oligodendroglioma with drop metastasis.

一只10岁已绝育的雌性拳师犬因左侧梨状叶疑似神经胶质瘤接受了立体定向放射治疗（SRT）。轴内病变在T2加权像上呈高信号，在T2液体衰减反转恢复序列（T2 FLAIR）上呈高信号，在T1加权像上呈低信号，且不摄取造影剂。每3个月进行一次磁共振成像（MRI）检查，在6个月复查时，左侧海马体和右侧梨状叶出现新病变，但无明显的临床神经功能进展。针对新病变开出了第二个SRT疗程。在第一个SRT疗程14个月后选择实施安乐死，尸检证实为少突胶质细胞瘤伴播散性转移。