Efford Christopher, Holdsworth Catherine, Donovan-Hall Margaret, Samuel Dinesh
Faculty of Environmental and Life Sciences, University of Southampton, UK.
University Hospitals Dorset, UK.
J Orthop. 2024 Aug 13;60:115-124. doi: 10.1016/j.jor.2024.08.003. eCollection 2025 Feb.
To examine the multi-factorial efficacy of day-zero ambulation following primary total hip arthroplasty.
MEDLINE, CINAHL, AMED, EMBASE and APA PsychInfo in accordance with PRISMA guidelines.
Studies were classified for study design and ranked in a hierarchy of evidence. Studies ranked excellent or good who followed a treatment pathway inclusive of day-zero ambulation were appraised using the appropriate content checklist (PRISMA, CONSORT, STROBE), CASP checklist and where possible for risk of bias using the appropriate tool (RoB 2.0, ROBINS-1). Results were produced using a narrative synthesis.
A total of 8 studies met inclusion criteria. Studies reported a consensus of a reduced length of hospital stay in pathways where day-zero ambulation was included, but with varying effect sizes. Findings suggested that day-zero ambulation may speed up return to function following THR. There was not enough evidence to provide synthesised results on financial efficiency, post-operative pain, or safety of day-zero ambulation via post-operative complications.
This systematic review reveals limitations within the literature base on day zero-ambulation. There are problems of concomitant interventions, methodological heterogeneity, and an abundance of research low in the evidence hierarchy. Day zero-ambulation shows promise in reducing length of hospital stay and there is suggestion that it accelerates functional recovery. However, to establish this with rigor, there is further need for high quality, prospective studies such as RCTs to examine the multi-factorial effect of day-zero ambulation, challenge existing theories and contribute to confident synthesised findings more useful to clinical decision makers.
探讨初次全髋关节置换术后零日活动的多因素疗效。
根据PRISMA指南检索MEDLINE、CINAHL、AMED、EMBASE和APA PsychInfo数据库。
根据研究设计对研究进行分类,并按证据等级排序。对遵循包括零日活动在内的治疗路径且证据等级为优秀或良好的研究,使用适当的内容清单(PRISMA、CONSORT、STROBE)、CASP清单进行评估,并尽可能使用适当工具(RoB 2.0、ROBINS-1)评估偏倚风险。采用叙述性综合分析得出结果。
共有8项研究符合纳入标准。研究报告称,在包含零日活动的治疗路径中,住院时间缩短已达成共识,但效应大小各异。研究结果表明,零日活动可能会加速全髋关节置换术后的功能恢复。没有足够的证据来综合分析零日活动在财务效率、术后疼痛或术后并发症导致的安全性方面的结果。
本系统综述揭示了关于零日活动的文献存在局限性。存在伴随干预、方法学异质性以及大量证据等级较低的研究等问题。零日活动在缩短住院时间方面显示出前景,且有迹象表明它能加速功能恢复。然而,为了严谨地证实这一点,还需要高质量的前瞻性研究,如随机对照试验,以检验零日活动的多因素效应,挑战现有理论,并为临床决策者提供更有用的可靠综合研究结果。