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深度学习用于腹主动脉瘤超声筛查的前瞻性临床评估

Prospective clinical evaluation of deep learning for ultrasonographic screening of abdominal aortic aneurysms.

作者信息

Chiu I-Min, Chen Tien-Yu, Zheng You-Cheng, Lin Xin-Hong, Cheng Fu-Jen, Ouyang David, Cheng Chi-Yung

机构信息

Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

出版信息

NPJ Digit Med. 2024 Oct 15;7(1):282. doi: 10.1038/s41746-024-01269-4.

DOI:10.1038/s41746-024-01269-4
PMID:39406888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11480325/
Abstract

Abdominal aortic aneurysm (AAA) often remains undetected until rupture due to limited access to diagnostic ultrasound. This trial evaluated a deep learning (DL) algorithm to guide AAA screening by novice nurses with no prior ultrasonography experience. Ten nurses performed 15 scans each on patients over 65, assisted by a DL object detection algorithm, and compared against physician-performed scans. Ultrasound scan quality, assessed by three blinded expert physicians, was the primary outcome. Among 184 patients, DL-guided novices achieved adequate scan quality in 87.5% of cases, comparable to the 91.3% by physicians (p = 0.310). The DL model predicted AAA with an AUC of 0.975, 100% sensitivity, and 97.8% specificity, with a mean absolute error of 2.8 mm in predicting aortic width compared to physicians. This study demonstrates that DL-guided POCUS has the potential to democratize AAA screening, offering performance comparable to experienced physicians and improving early detection.

摘要

腹主动脉瘤(AAA)通常在破裂前都未被发现,因为诊断性超声检查的机会有限。本试验评估了一种深度学习(DL)算法,以指导没有超声检查经验的新手护士进行AAA筛查。10名护士在DL目标检测算法的辅助下,对65岁以上的患者每人进行15次扫描,并与医生进行的扫描结果进行比较。由三名不知情的专家医生评估的超声扫描质量是主要结果。在184名患者中,DL指导的新手在87.5%的病例中获得了足够的扫描质量,与医生的91.3%相当(p = 0.310)。DL模型预测AAA的AUC为0.975,灵敏度为100%,特异性为97.8%,与医生相比,预测主动脉宽度的平均绝对误差为2.8毫米。这项研究表明,DL指导的床旁超声检查有潜力使AAA筛查民主化,其性能与经验丰富的医生相当,并能改善早期检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a718/11480325/5a07f1980c50/41746_2024_1269_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a718/11480325/ad4174c84839/41746_2024_1269_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a718/11480325/5a07f1980c50/41746_2024_1269_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a718/11480325/ad4174c84839/41746_2024_1269_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a718/11480325/5a07f1980c50/41746_2024_1269_Fig2_HTML.jpg

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High-Throughput Precision Phenotyping of Left Ventricular Hypertrophy With Cardiovascular Deep Learning.高通量精准表型分析左心室肥厚的心血管深度学习方法。
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The utility of point of care ultrasonography (POCUS).床旁超声检查(POCUS)的效用。
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Deep Learning Assisted Detection of Abdominal Free Fluid in Morison's Pouch During Focused Assessment With Sonography in Trauma.深度学习辅助在创伤超声重点评估中检测莫里森陷凹内的腹腔游离液体。
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