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不同反馈设备在心脏骤停患者生存中的作用:系统评价与荟萃分析

The Role of Different Feedback Devices in the Survival of Patients in Cardiac Arrest: Systematic Review with Meta-Analysis.

作者信息

Gambolò Luca, Di Fronzo Pasquale, Ristagno Giuseppe, Biserni Sofia, Milazzo Martina, Socaci Delia Marta, Sarli Leopoldo, Artioli Giovanna, Bonacaro Antonio, Stirparo Giuseppe

机构信息

SIMED-Società Italiana di Medicina e Divulgazione Scientifica, 43121 Parma, Italy.

Local Health Unit of Piacenza, Ospedale Guglielmo da Saliceto, 29122 Piacenza, Italy.

出版信息

J Clin Med. 2024 Oct 8;13(19):5989. doi: 10.3390/jcm13195989.

Abstract

Cardiac arrest is a critical condition affecting approximately 1 in every 1000 people in Europe. Feedback devices have been developed to enhance the quality of chest compressions during CPR, but their clinical impact remains uncertain. This study aims to evaluate the effect of feedback devices on key clinical outcomes in adult patients experiencing both out-of-hospital (OHCA) and in-hospital cardiac arrest (IHCA). The primary objective is to assess their impact on the return of spontaneous circulation (ROSC); secondary objectives include the evaluation of neurological status and survival to discharge. A systematic review was conducted following PRISMA guidelines, utilizing databases including PubMed, Scopus, Web of Science, and Embase. Studies published between 2000 and 2023 comparing CPR with and without the use of feedback devices were included. A fixed-effects network meta-analysis was performed for ROSC and survival, while a frequentist meta-analysis was conducted for neurological outcomes. Twelve relevant studies met the inclusion criteria. The meta-analysis results showed that the use of audiovisual feedback devices significantly increases the likelihood of ROSC (OR 1.26, 95% CI 1.13-1.41, < 0.0001) and survival (OR 1.52, 95% CI 1.27-1.81, < 0.0001) compared to CPR without feedback. However, the effect of metronomes did not reach statistical significance. Feedback devices, particularly audiovisual ones, are associated with improved clinical outcomes in cardiac arrest patients. Their use should be encouraged in both training settings and real-life emergency scenarios to enhance survival rates and ROSC. However, further studies are needed to confirm long-term impacts and to explore the potential benefits of metronomes.

摘要

心脏骤停是一种危急状况,在欧洲每1000人中约有1人受其影响。反馈设备已被开发出来,以提高心肺复苏(CPR)期间胸外按压的质量,但其临床影响仍不确定。本研究旨在评估反馈设备对院外心脏骤停(OHCA)和院内心脏骤停(IHCA)成年患者关键临床结局的影响。主要目标是评估其对自主循环恢复(ROSC)的影响;次要目标包括评估神经状态和出院生存率。按照PRISMA指南进行了系统评价,利用了包括PubMed、Scopus、科学网和Embase在内的数据库。纳入了2000年至2023年发表的比较使用和不使用反馈设备进行心肺复苏的研究。对ROSC和生存率进行了固定效应网络荟萃分析,对神经学结局进行了频率学派荟萃分析。十二项相关研究符合纳入标准。荟萃分析结果表明,与无反馈的心肺复苏相比,使用视听反馈设备显著增加了ROSC的可能性(比值比1.26,95%置信区间1.13 - 1.41,<0.0001)和生存率(比值比1.52,95%置信区间1.27 - 1.81,<0.0001)。然而,节拍器的效果未达到统计学显著性。反馈设备,尤其是视听反馈设备,与心脏骤停患者临床结局的改善相关。在培训环境和实际紧急情况下都应鼓励使用它们,以提高生存率和ROSC。然而,需要进一步研究来确认长期影响并探索节拍器的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c021/11477487/b0ec859b116e/jcm-13-05989-g001.jpg

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