使用第一秒用力呼气容积（FEV）与肺总量（TLC）来测量限制性肺疾病的严重程度。
Measuring Restrictive Lung Disease Severity Using FEV vs TLC.
作者信息
Vazquez-Nieves Rebeca, Fonseca-Ferrer Vanessa, Irizarry-Nieves Juan, Adorno-Fontanez Edgardo, Rodriguez-Cintron William
机构信息
Veterans Affairs Caribbean Healthcare System, San Juan, Puerto Rico.
University of Puerto Rico School of Medicine, San Juan.
出版信息
Fed Pract. 2024 Jul;41(7):222-227. doi: 10.12788/fp.0481. Epub 2024 Jul 16.
BACKGROUND
No clear parameters currently exist to grade severity in restrictive lung disease as for other ventilatory diseases. This article evaluates whether total lung capacity (TLC) or forced expiratory volume in 1 second (FEV) better correlates with the symptomatology of patients with restrictive lung disease.
METHODS
A retrospective review of 6461 patient records at Veterans Affairs Caribbean Healthcare System in Puerto Rico was conducted, and 414 patients met the inclusion criteria. Pulmonary function test, Modified Medical Research Council Dyspnea Scale, FEV, and TLC data were collected for each patient.
RESULTS
We identified a stronger correlation between FEV ( = 0.25, < .001) vs TLC ( = 0.15, < .001) when related to the degree of dyspnea as measured with the Modified Medical Research Council Dyspnea Scale.
CONCLUSIONS
Results of this study suggest that compared with TLC, FEV may provide a more accurate measure of restrictive lung disease severity. Further research should look for more accurate measures of patient dyspnea in restrictive lung disease.
背景
目前尚无明确的参数可用于对限制性肺病的严重程度进行分级，而其他通气性疾病则有相应分级参数。本文评估了肺总量（TLC）或一秒用力呼气容积（FEV）与限制性肺病患者症状的相关性是否更强。
方法
对波多黎各退伍军人事务加勒比医疗系统的6461份患者记录进行回顾性研究，414名患者符合纳入标准。收集了每位患者的肺功能测试、改良医学研究委员会呼吸困难量表、FEV和TLC数据。
结果
当与改良医学研究委员会呼吸困难量表所测量的呼吸困难程度相关时，我们发现FEV（r = 0.25，P <.001）与TLC（r = 0.15，P <.001）相比，相关性更强。
结论
本研究结果表明，与TLC相比，FEV可能是评估限制性肺病严重程度更准确的指标。进一步的研究应寻找评估限制性肺病患者呼吸困难更准确的方法。
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