Trakya University School of Medicine, Edime, Turkey.
Department of Medical Oncology, Kırklareli Education and Research Hospital, Turkey.
J Cancer Res Ther. 2024 Jul 1;20(5):1615-1617. doi: 10.4103/jcrt.jcrt_1963_22. Epub 2023 Apr 4.
Primary signet ring cell carcinoma (SRCC) of the breast is a rare and aggressive type of breast cancer characterized by increased intracellular mucin production. It has a high risk of metastasis and poor prognosis compared to other breast cancer types. We report a 56-year-old woman with primary SRCC of the breast who first presented with retraction on her left breast. Radiological examination revealed a mass that causes the retraction. The patient underwent left modified radical mastectomy, and pathology results showed a 70% signet ring cell pattern. Chemotherapy consists of an adriamycin-cyclophosphamide regimen administered. in this case, we aim to review the literature on this topic and inform the physicians.
原发性乳腺印戒细胞癌(SRCC)是一种罕见且侵袭性强的乳腺癌,其特征是细胞内粘蛋白产生增加。与其他乳腺癌类型相比,它具有更高的转移风险和更差的预后。我们报告了一例 56 岁女性,患有原发性乳腺 SRCC,最初表现为左侧乳房回缩。影像学检查显示引起回缩的肿块。患者接受了左侧改良根治性乳房切除术,病理结果显示 70%为印戒细胞模式。化疗方案包括阿霉素-环磷酰胺方案。在这种情况下,我们旨在回顾该主题的文献并为医生提供信息。