Wood B, Currie J, Breen K
Med J Aust. 1986 Jan 6;144(1):12-6. doi: 10.5694/j.1326-5377.1986.tb113623.x.
Thirty-two cases of Wernicke's encephalopathy were admitted to hospital for treatment in a period of 33 months; this represented a relatively low incidence in total hospital admissions. Thiamin status was deficient, borderline and normal in 21 (66%), five (16%) and six (19%) patients, respectively, and responded immediately to treatment in those who had abnormal thiamin status. Ophthalmoplegia responded rapidly to treatment. Nystagmus, ataxia, disturbance of mental function and peripheral neuropathy responded incompletely to treatment in both the short-and the long-term. The overall setting for the development of Wernicke's encephalopathy appears to be chronic alcohol abuse, accompanied by cerebral "atrophy" and liver disease, but often without gross evidence of malnutrition.
在33个月的时间里，有32例韦尼克脑病患者入院接受治疗；这在医院总入院人数中所占比例相对较低。硫胺素状态缺乏、临界和正常的患者分别为21例（66%）、5例（16%）和6例（19%），硫胺素状态异常的患者对治疗立即产生反应。眼肌麻痹对治疗反应迅速。眼球震颤、共济失调、精神功能障碍和周围神经病变在短期和长期内对治疗的反应均不完全。韦尼克脑病发生的总体背景似乎是慢性酒精滥用，伴有脑“萎缩”和肝病，但往往没有明显的营养不良证据。
