N-亚硝胺与尼日利亚的习惯性饮品及癌症

N-nitrosamines and Nigerian habitual drinks, and cancer.

作者信息

Maduagwu E N, Uhegbu F O

出版信息

Carcinogenesis. 1986 Jan;7(1):149-51. doi: 10.1093/carcin/7.1.149.

DOI:10.1093/carcin/7.1.149

Abstract

Commercially available samples of Nigerian lager beers and bottled palm wine, and of root cuttings of medicinal plants, assayed for volatile N-nitroso compounds and nitrosatable entities, respectively, by chromatographic, chemiluminescence, colorimetric, derivatisation and nitrosation methods, contained nitrosodimethylamine (0.2-2.3 micrograms/kg; mean, 0.9 micrograms/kg) only in the drinks, and dimethylamine (DMA) and piperidine (1 mg/kg as DMA) in the roots.

摘要

分别采用色谱法、化学发光法、比色法、衍生化法和亚硝化法，对市售尼日利亚贮藏啤酒、瓶装棕榈酒以及药用植物的根茎插条进行挥发性N-亚硝基化合物和可亚硝化物质的检测，结果发现仅在饮料中含有亚硝基二甲胺（0.2 - 2.3微克/千克；平均为0.9微克/千克），而在根茎中含有二甲胺（DMA）和哌啶（以DMA计为1毫克/千克）。