>From the Nephrology, Dialysis and Transplantation Service, Las Higueras Hospital, Talcahuano, Chile; and the Departamento de Medicina Interna, Facultad de Medicina, Universidad de Concepción, Concepción, Chile.
Exp Clin Transplant. 2024 Sep;22(9):717-720. doi: 10.6002/ect.2024.0182.
Anticoagulant-related nephropathy is an increasingly recognized entity, characterized by the presence of hematuria in the context of a supratherapeutic international normalized ratio with the development of secondary acute kidney injury, which may require renal replacement therapy and may progress to chronic kidney disease. We present the case of a 63-year-old patient who started anticoagulant therapy with acenocoumarol 2 months after her kidney transplant and presented with graft dysfunction concomitant to a supratherapeutic international normalized ratio.
抗凝相关肾病是一种日益受到认识的病症,其特征是在国际标准化比值高于治疗范围并出现继发性急性肾损伤的情况下出现血尿,可能需要肾脏替代治疗,并可能进展为慢性肾脏病。我们报告 1 例 63 岁患者,肾移植后 2 个月开始用华法林进行抗凝治疗,出现移植肾功能障碍和国际标准化比值高于治疗范围。