Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University Chandigarh, Chandigarh, 160014, India.
Department of Mechanical Engineering, University Institute of Engineering and Technology, Panjab University, Chandigarh, 160014, India.
Mikrochim Acta. 2024 Oct 21;191(11):684. doi: 10.1007/s00604-024-06762-x.
As a class of carbon-based nanomaterials, carbon dots (CDs) have gained a lot of interest for a variety of applications. They offer distinctive optical, chemical, and structural characteristics along with favourable attributes such as low cost, availability of abundant functional groups, remarkable chemical inertness, high stability, exceptional biocompatibility, and ecofriendliness. This review discusses synthesis methods, structural characteristics, and surface modifications of CDs, specific for pathogen detection. Furthermore, it delves into the mechanisms that govern the interaction between pathogens and CDs. In addition, the study explores the use of CDs in a number of detection modalities, such as optical, electrochemical, and electrochemiluminescence, emphasising real-time pathogen monitoring. Moreover, both the challenges and opportunities related to the application of CDs-based detection and imaging methods are highlighted in field and clinical contexts.
作为一类碳基纳米材料,碳点(CDs)因其在各种应用中的独特光学、化学和结构特性,以及低成本、丰富的官能团可用性、显著的化学惰性、高稳定性、出色的生物相容性和环境友好性等优点,引起了广泛关注。本文综述了用于病原体检测的 CDs 的合成方法、结构特征和表面修饰,特别讨论了用于病原体检测的 CDs 的合成方法、结构特征和表面修饰。此外,还深入探讨了控制病原体与 CDs 相互作用的机制。此外,研究还探讨了 CDs 在多种检测模式中的应用,如光学、电化学和电致化学发光,强调了实时病原体监测。此外,还强调了在现场和临床环境中应用基于 CDs 的检测和成像方法所面临的挑战和机遇。