Melamed M R, Enker W E, Banner P, Janov A J, Kessler G, Darzynkiewicz Z
Dis Colon Rectum. 1986 Mar;29(3):184-6. doi: 10.1007/BF02555020.
Flow cytometry DNA measurements were carried out on colorectal carcinomas from a series of 33 patients who have since been followed for three to four years. The tumors could be subclassified by this technique into 15 that had near-diploid DNA and 18 that were aneuploid. Prior reports had suggested that the near-diploid tumors carry a better prognosis than aneuploid tumors, but in this study the distribution by Dukes' stage and survival were the same in both groups.
对33例结直肠癌患者的肿瘤进行了流式细胞术DNA检测,这些患者随后被随访了三到四年。通过该技术,肿瘤可被分为15例近二倍体DNA肿瘤和18例非整倍体肿瘤。先前的报告表明,近二倍体肿瘤的预后比非整倍体肿瘤好,但在本研究中,两组患者在Dukes分期和生存率方面的分布是相同的。