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椰枣:一种对男性生殖系统有重大影响的天然化合物。

Ceratonia Siliqua L: A Natural Compound with Big Impact on Male Reproductive System.

机构信息

MSc of Medical Physiology Graduated from Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Am J Mens Health. 2024 Sep-Oct;18(5):15579883241290835. doi: 10.1177/15579883241290835.

DOI:10.1177/15579883241290835
PMID:39434540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11504079/
Abstract

Herbal products with antioxidant properties have gained attention for their potential impact on male reproductive health. One such botanical, (commonly known as carob), has been empirically used by infertile men in Iran and Turkey. Carob, a pod-bearing tree native to the Mediterranean, exhibits promising therapeutic potential for various aspects of male reproductive health. Carob consumption may positively affect sperm count, motility, and morphology in infertile men. The proposed mechanisms involve antioxidant activity, improved blood flow, and enhanced energy production within sperm. Carob's richness in antioxidants like polyphenols and flavonoids might counteract oxidative stress, a major contributor to sperm dysfunction. Carob may influence male sex hormones by potentially stimulating testosterone production and inhibiting estrogen conversion. While carob demonstrates promise as a natural supplement for male fertility, more robust research is necessary to solidify its therapeutic role. This exploration could pave the way for the development of novel dietary or nutraceutical interventions to address male infertility. While preliminary research suggests positive effects on sperm health and potential hormonal influence, robust clinical trials are needed to solidify carob's therapeutic efficacy. This exploration paves the way for future research on carob as a natural supplement and potentially opens doors for novel dietary or nutraceutical interventions to address male infertility.

摘要

具有抗氧化特性的草药产品因其对男性生殖健康的潜在影响而受到关注。一种这样的植物药,(通常被称为角豆),已经在伊朗和土耳其的不育男性中被经验性地使用。角豆是一种原产于地中海地区的豆荚树,具有治疗男性生殖健康各个方面的有前途的治疗潜力。角豆的消费可能会对不育男性的精子数量、活力和形态产生积极影响。提出的机制涉及抗氧化活性、改善血液流动和提高精子内的能量产生。角豆富含多酚和类黄酮等抗氧化剂,可能对抗氧化应激,这是精子功能障碍的主要原因。角豆可能通过潜在地刺激睾丸激素的产生和抑制雌激素的转化来影响男性性激素。虽然角豆作为男性生育力的天然补充剂具有很大的希望,但需要更多的强有力的研究来确定其治疗作用。这种探索为开发新的饮食或营养干预措施来解决男性不育症铺平了道路。虽然初步研究表明对精子健康有积极影响,并且可能对激素有影响,但需要进行强有力的临床试验来确定角豆的治疗效果。这种探索为角豆作为天然补充剂的未来研究开辟了道路,并可能为解决男性不育症的新的饮食或营养干预措施打开大门。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/2b6262685a47/10.1177_15579883241290835-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/913dac60e0dc/10.1177_15579883241290835-img2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/1dd3b6ccc4d5/10.1177_15579883241290835-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/bc58ecc6c750/10.1177_15579883241290835-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/2b6262685a47/10.1177_15579883241290835-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/913dac60e0dc/10.1177_15579883241290835-img2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/1dd3b6ccc4d5/10.1177_15579883241290835-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/bc58ecc6c750/10.1177_15579883241290835-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e96/11504079/2b6262685a47/10.1177_15579883241290835-fig3.jpg

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Effect of Carob Supplement on Spermogram Parameters and Sexual Function of Infertile Men Referred to the Infertility Center, Hamadan, Iran, 2019: A Randomized Controlled Trial.2019年,角豆补充剂对伊朗哈马丹不孕症中心不育男性精液参数和性功能的影响:一项随机对照试验
J Family Reprod Health. 2023 Sep;17(3):142-150. doi: 10.18502/jfrh.v17i3.13537.
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Effect of Carob and Ginseng Supplements on Semen Analysis Parameters, Sexual Function, and Sex Hormones in Infertile Men: Double-Blind, Randomized Controlled Trial Study.
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Iran J Nurs Midwifery Res. 2024 Jan 9;29(1):113-119. doi: 10.4103/ijnmr.ijnmr_460_21. eCollection 2024 Jan-Feb.
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