Pilehvari Shamim, Masoumi Seyedeh Zahra, Bahar Tayebeh G, Kazemi Farideh, Moradkhani Shirin, Maleki Parvin
Fertility and Infertility Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Mother and Child Care Research Center, Midwifery and Reproductive Department, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.
Iran J Nurs Midwifery Res. 2024 Jan 9;29(1):113-119. doi: 10.4103/ijnmr.ijnmr_460_21. eCollection 2024 Jan-Feb.
Infertility is one of the most common problems in the world; there is a growing demand for herbal medicines to treat infertility-related problems.
A randomized controlled trial with three groups was conducted, each with 30 participants. The first group was administered 1.5 grams of Carob daily, the second group was administered 1.5 grams of Ginseng daily, and the third group received a placebo. The treatment was administered for 12 weeks, and before and after the intervention, semen parameters, testosterone, prolactin, luteinizing hormone, follicle-stimulating hormone, thyroid hormones, and sexual function were evaluated. Sexual function was assessed using the International Index of Erectile Function Questionnaire.
The mean (SD) age of participants was 34.83 (6.22), 34.60 (5.78), and 33.67 (5.82) years in Carob, Ginseng, and Placebo groups, respectively. The results showed that in the Carob group, the normal volume of semen (Z = 3.05, = 0.02) and the normal shape of sperm (Z = 2.97, = 0.01) increased significantly compared to the control group. In the Ginseng group, the normal volume (Z = 3.90, = 0.001) and the normal viscosity of semen (Z = 2.36, = 0.01) increased significantly compared to the control group.The Carob group showed a significant increase in normal sperm counts and testosterone hormone levels (Z = 2.81, = 0.05). The Ginseng group demonstrated a significant improvement in orgasm function (H = 6.14, = 0.04) and the total score of the International Index of Erectile Function (IIEF) (H = 5.8, = 0.05).
Carob supplements are suggested to enhance some semen parameters and male sex hormones. For infertile men, Ginseng can be beneficial in improving sexual function.
不孕症是全球最常见的问题之一；治疗不孕症相关问题的草药需求日益增长。
进行了一项三组随机对照试验，每组30名参与者。第一组每天服用1.5克角豆，第二组每天服用1.5克人参，第三组服用安慰剂。治疗持续12周，在干预前后，评估精液参数、睾酮、催乳素、黄体生成素、促卵泡激素、甲状腺激素和性功能。性功能使用国际勃起功能指数问卷进行评估。
角豆组、人参组和安慰剂组参与者的平均（标准差）年龄分别为34.83（6.22）岁、34.60（5.78）岁和33.67（5.82）岁。结果显示，与对照组相比，角豆组精液正常体积（Z = 3.05，P = 0.02）和精子正常形态（Z = 2.97，P = 0.01）显著增加。与人参组相比，人参组精液正常体积（Z = 3.90，P = 0.001）和正常粘度（Z = 2.36，P = 0.01）显著增加。角豆组正常精子数量和睾酮激素水平显著增加（Z = 2.81，P = 0.05）。人参组性高潮功能（H = 6.14，P = 0.04）和国际勃起功能指数（IIEF）总分（H = 5.8，P = 0.05）有显著改善。
建议食用角豆补充剂以改善一些精液参数和男性性激素。对于不育男性，人参可能有助于改善性功能。
