Editorial: Understanding the mesenchymal to epithelial transition: a much needed angle for epithelial mesenchymal plasticity.
作者信息
Alotaibi Hani, Meuwissen Ralph, Sayan A Emre
机构信息
Izmir International Biomedicine and Genome Institute, Dokuz Eylül University, Izmir, Türkiye.
Basic and Translational Research Program, Izmir Biomedicine and Genome Center, Izmir, Türkiye.
出版信息
Front Cell Dev Biol. 2024 Oct 7;12:1497515. doi: 10.3389/fcell.2024.1497515. eCollection 2024.
Abstract
摘要
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The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.ZEB2 依赖性 EMT 转录程序通过激活结直肠癌中的核苷酸切除修复基因 ERCC1 和 ERCC4 来驱动治疗抵抗。
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