Weiler M A, Jobe T H, Nasr S J, Pandey G, Altman E G
J Clin Psychiatry. 1986 Feb;47(2):60-2.
To assess the relationship of baseline cortisol to the 1 mg dexamethasone suppression test (DST), 4 p.m. baseline and 4 p.m. postdexamethasone blood samples were drawn on 52 consecutive depressed outpatients. Baseline cortisol correlated significantly with post-DST values, and baseline levels above 15 micrograms/dl predicted DST nonsuppression with 90.4% accuracy. These data lend some support to the usefulness of baseline cortisol determination in depressed outpatients in whom a full DST may be difficult.
为评估基线皮质醇与1毫克地塞米松抑制试验（DST）之间的关系，对52例连续的门诊抑郁症患者于下午4点采集基线血样，并于下午4点给予地塞米松后采集血样。基线皮质醇与地塞米松抑制试验后的值显著相关，基线水平高于15微克/分升时预测地塞米松抑制试验不被抑制的准确率为90.4%。这些数据为在难以进行完整地塞米松抑制试验的门诊抑郁症患者中测定基线皮质醇的有用性提供了一定支持。
