Bernstein J P, Chung S Y, Avila K S
J Clin Psychiatry. 1982 Dec;43(12):476-8.
The cortisol suppression index (CSI) is a ratio of pre- to postdexamethasone plasma cortisol concentrations. In a sample of 24 psychiatric inpatients, an 8 a.m. CSI detected 66% of patients with major depression. Further studies with larger samples and additional controls, including normal subjects, are suggested to validate these prospective findings. This index may serve as a useful and more practical way of detecting major depression in outpatients.
皮质醇抑制指数（CSI）是地塞米松给药前后血浆皮质醇浓度的比值。在24名精神科住院患者的样本中，上午8点的CSI检测出66%的重度抑郁症患者。建议进行更大样本量并纳入包括正常受试者在内的更多对照的进一步研究，以验证这些前瞻性研究结果。该指数可能是检测门诊患者重度抑郁症的一种有用且更实用的方法。
