University of Bristol, Bristol Medical School, Bristol, United Kingdom.
Oxford University Hospitals NHS Trust, Oxford, United Kingdom.
PLoS One. 2024 Oct 23;19(10):e0311668. doi: 10.1371/journal.pone.0311668. eCollection 2024.
Osteoarthritis is a leading cause of joint pain and disability. Intra-articular corticosteroid injections (IACs) are often used in primary care once other recommended treatments have failed. Evidence shows that IACs provide short-term relief of osteoarthritis symptoms, yet little is known about patients' and primary care clinicians' experiences and beliefs about their use. We explored patients' and primary care clinicians' views about IACs, including the benefits, disadvantages, perceived risks of treatment, when they are used, and factors that affect decision-making.
We conducted individual interviews with patients and primary care clinicians and used inductive thematic analysis to investigate their views and experiences of intra-articular corticosteroid injections for osteoarthritis (IACs).
We interviewed 38 patients and 19 primary care clinicians. We identified 6 patient themes: variation in access; awareness of IACs; views of risk and trust; effectiveness of IACs; variation in onset and effect duration; and an alternative to undesirable treatments. In the interviews with clinicians, we identified an overarching theme of caution and competence, which included eight subthemes: confidence and (dis)comfort with practical procedures; risk of adverse outcomes; training; uncertainty about evidence and guidelines; technical uncertainties; IACs use on the osteoarthritis pathway; perceived benefits and impacts of IACs; and the possibility of placebo.
Patients and clinicians valued IACs' potential to relieve symptoms and improve quality of life. Variability in patients' access to treatment appears related to clinicians' confidence in delivering injections and their concerns about the evidence base. Variation in dose frequency and timing reflect clinicians' uncertainty about current guidance. Despite variation in effectiveness patients preferred IACs to other forms of pain medication and to delay or avoid surgery. IACs were mostly used as an adjunct treatment before surgery was offered. These findings can inform further research into the effectiveness of IACs and improvements in information and guidance.
骨关节炎是导致关节疼痛和残疾的主要原因。一旦其他推荐的治疗方法失败,关节内皮质类固醇注射(IAC)通常在初级保健中使用。有证据表明,IAC 可以短期缓解骨关节炎症状,但人们对患者和初级保健临床医生对其使用的经验和看法知之甚少。我们探讨了患者和初级保健临床医生对 IAC 的看法,包括治疗的益处、弊端、感知风险、何时使用以及影响决策的因素。
我们对患者和初级保健临床医生进行了单独访谈,并使用归纳主题分析来调查他们对关节内皮质类固醇注射治疗骨关节炎(IAC)的看法和经验。
我们采访了 38 名患者和 19 名初级保健临床医生。我们确定了 6 个患者主题:获得途径的差异;对 IAC 的认识;风险和信任的看法;IAC 的有效性;发作和效果持续时间的差异;以及对不理想治疗的替代方案。在对临床医生的访谈中,我们确定了一个谨慎和能力的总主题,其中包括 8 个副标题:对实际操作的信心和(不适);不良后果的风险;培训;对证据和指南的不确定性;技术上的不确定性;IAC 在骨关节炎治疗途径上的使用;IAC 的预期收益和影响;以及安慰剂的可能性。
患者和临床医生重视 IAC 缓解症状和提高生活质量的潜力。患者接受治疗的途径存在差异,这似乎与临床医生对注射的信心以及他们对证据基础的担忧有关。剂量频率和时间的差异反映了临床医生对当前指南的不确定性。尽管疗效存在差异,但患者还是更喜欢 IAC 而不是其他形式的止痛药,也更喜欢延迟或避免手术。IAC 主要用作手术前的辅助治疗。这些发现可以为进一步研究 IAC 的有效性以及改进信息和指导提供依据。