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营养状况和饮食习惯与女性不孕症发生的关联。一项病例对照研究。

Associations of nutritional status and dietary habits with the development of female infertility. A case-control study.

作者信息

Martín-Manchado Laura, Moya-Yeste Antonio Manuel, Sánchez-Sansegundo Miriam, Hurtado-Sánchez José Antonio, Gil-Miralles Regina Andrea, Tuells José, Zaragoza-Martí Ana

机构信息

Department of Nursing, Faculty of Health Sciences, University of Alicante, Alicante, Spain.

Gynaecology and Obstetrics Service, Hospital IMED de Levante, Benidorm, Spain.

出版信息

Front Nutr. 2024 Oct 9;11:1476784. doi: 10.3389/fnut.2024.1476784. eCollection 2024.

Abstract

INTRODUCTION

Female infertility is a multifactorial condition influenced by lifestyle and dietary factors. Understanding the relationship between nutritional status, dietary habits, and infertility could provide insights for targeted interventions.

METHODS

A case-control study was conducted in health centers and hospitals in Alicante, Spain. The study included 60 infertile and 30 fertile women aged 18-40, selected through consecutive sampling. Data on body composition and dietary intake were collected and analyzed.

RESULTS

Infertile women exhibited significantly lower muscle mass ( = 0.005) and larger hip circumference ( = 0.034) compared to fertile women. Additionally, a significant association was found between high red meat consumption and an increased risk of female infertility ( = 0.011).

DISCUSSION

These results suggest that body composition and dietary habits, particularly muscle mass and red meat intake, play a key role in female fertility. Interventions aimed at improving muscle mass, reducing localized body fat, and limiting red meat consumption may enhance fertility outcomes. Further longitudinal research is needed to confirm these findings across diverse populations.

摘要

引言

女性不孕症是一种受生活方式和饮食因素影响的多因素疾病。了解营养状况、饮食习惯与不孕症之间的关系可为针对性干预提供思路。

方法

在西班牙阿利坎特的健康中心和医院开展了一项病例对照研究。该研究纳入了60名年龄在18至40岁之间的不孕女性和30名生育能力正常的女性,通过连续抽样选取。收集并分析了身体成分和饮食摄入的数据。

结果

与生育能力正常的女性相比,不孕女性的肌肉量显著更低( = 0.005),臀围更大( = 0.034)。此外,发现大量食用红肉与女性不孕风险增加之间存在显著关联( = 0.011)。

讨论

这些结果表明,身体成分和饮食习惯,特别是肌肉量和红肉摄入量,在女性生育能力中起关键作用。旨在增加肌肉量、减少局部体脂和限制红肉消费的干预措施可能会改善生育结果。需要进一步开展纵向研究,以在不同人群中证实这些发现。

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Dietary Patterns and Fertility.饮食模式与生育能力。
Biology (Basel). 2024 Feb 19;13(2):131. doi: 10.3390/biology13020131.
2
Association between waist circumference and female infertility in the United States.美国腰围与女性不孕的关系。
PLoS One. 2023 Dec 20;18(12):e0295360. doi: 10.1371/journal.pone.0295360. eCollection 2023.
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Gestational diabetes mellitus - A metabolic and reproductive disorder.妊娠糖尿病——一种代谢和生殖紊乱疾病。
Biomed Pharmacother. 2021 Nov;143:112183. doi: 10.1016/j.biopha.2021.112183. Epub 2021 Sep 21.

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