Suresh Mythili, Mukundan Sri Kessav, Rajasekar Sivaraman, Gokulakrishnan Sangavi, Purushothaman Navesh, Sethuraman Sakthi Priyadarsini
Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of Science and Technology, Chennai, IND.
Cureus. 2024 Sep 23;16(9):e69982. doi: 10.7759/cureus.69982. eCollection 2024 Sep.
Lam. (Moringaceae) is an indigenous tree extensively used as a nutrient and an antioxidant. In addition to its medicinal attributes, it possesses a promising role in moisturizing and cleansing the skin.
Our study aims to formulate an herbal cream from oil and evaluate its antimicrobial and anti-inflammatory activity.
In the present study, oil was extracted from the seed kernels and formulated into an herbal cream, and the antimicrobial and anti-inflammatory activity was evaluated. Among the three formulations M1, M2, and M3, the formulation M1 was homogenous, more stable, and non-greasy with constant pH. M1 was subjected to further antimicrobial studies and anti-inflammatory studies by the agar-well diffusion technique and albumin denaturation assays, respectively.
seed kernel oil cream exhibited the highest antibacterial effect against and and the results were compared to the standard gentamycin. Moreover, M1 showed remarkable anti-inflammatory activity with an IC value of 124.5 μg/mL.
The results show that the formulated cream will be efficient in its multipurpose activity. The current study validates the antibacterial and anti-inflammatory potential of seed kernel oil cream.
辣木（辣木科）是一种本土树木，被广泛用作营养剂和抗氧化剂。除了其药用特性外，它在滋润和清洁皮肤方面也具有重要作用。
我们的研究旨在用辣木籽油配制一种草本乳膏，并评估其抗菌和抗炎活性。
在本研究中，从辣木籽仁中提取油并配制成草本乳膏，然后评估其抗菌和抗炎活性。在三种配方M1、M2和M3中，配方M1均匀、更稳定且不油腻，pH值恒定。分别通过琼脂孔扩散技术和白蛋白变性试验对M1进行进一步的抗菌研究和抗炎研究。
辣木籽仁油乳膏对[具体菌种1]和[具体菌种2]表现出最高的抗菌效果，结果与标准庆大霉素进行了比较。此外，M1显示出显著的抗炎活性，IC值为124.5μg/mL。
结果表明，配制的乳膏在其多功能活性方面将是有效的。当前研究验证了辣木籽仁油乳膏的抗菌和抗炎潜力。
