Bennett Josiah, Chandrasekhar Sanjay, Woods Edward, McLean Patrick, Newman Noah, Montelaro Brett, Hassan Virk Hafeez Ul, Alam Mahboob, Sharma Samin K, Jned Hani, Khawaja Muzamil, Krittanawong Chayakrit
Department of Internal Medicine, Emory University, Atlanta, GA 30322, USA.
Harrington Heart & Vascular Institute, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Future Cardiol. 2024;20(14):755-778. doi: 10.1080/14796678.2024.2416817. Epub 2024 Oct 24.
Functional coronary angiography (FCA) is a novel modality for assessing the physiology of coronary lesions, going beyond anatomical visualization by traditional coronary angiography. FCA incorporates indices like fractional flow reserve (FFR) and instantaneous wave-free ratio (IFR), which utilize pressure measurements across coronary stenoses to evaluate hemodynamic impacts and to guide revascularization strategies. In this review, we present traditional and evolving modalities and uses of FCA. We will also evaluate the existing evidence and discuss the applicability of FCA in various clinical scenarios. Finally, we provide insight into emerging evidence, current challenges, and future directions in FCA.
功能性冠状动脉造影（FCA）是一种评估冠状动脉病变生理学的新型方法，超越了传统冠状动脉造影的解剖学可视化。FCA纳入了诸如血流储备分数（FFR）和瞬时无波比值（IFR）等指标，这些指标利用跨冠状动脉狭窄处的压力测量来评估血流动力学影响并指导血运重建策略。在本综述中，我们介绍了FCA的传统和不断发展的方法及用途。我们还将评估现有证据，并讨论FCA在各种临床场景中的适用性。最后，我们深入探讨了FCA的新出现证据、当前挑战及未来方向。
