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在一个全国性的健康维护组织中开发和验证电子虚弱指数。

Development and validation of an electronic frailty index in a national health maintenance organization.

机构信息

Meuhedet Health Maintenance Organization (HMO), Tel-Aviv, Israel.

The Joint-Eshel Organization, Jerusalem, Israel.

出版信息

Aging (Albany NY). 2024 Oct 24;16(20):13025-13038. doi: 10.18632/aging.206141.

DOI:10.18632/aging.206141
PMID:39448091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11552639/
Abstract

BACKGROUND

Frailty constitutes a major factor that puts the elderly at risk of health and functional deterioration.

OBJECTIVES

To develop and validate an Electronic Frailty Index based on electronic data routinely collected in the HMO.

STUDY DESIGN AND SETTING

A retrospective cohort of the HMO members.

PARTICIPANTS

120,986 patients, aged 65 years and over at the beginning of 2023.

PREDICTORS

A cumulative frailty index including 36 medical, functional, and social deficits.

OUTCOMES

One-year all-cause mortality or hospitalization.

STATISTICAL ANALYSIS

One-year hazard ratios were estimated for composite outcome of mortality or hospitalization using multivariable hierarchical Cox regression.

RESULTS

The mean EFI score increased with the Social Security Nursing Benefit. Compared to fit patients, mild, moderate, and severe frailty patients had 2.07, 3.35, and 4.4-fold increased risks of mortality or hospitalization, after controlling for covariates.

CONCLUSIONS

The findings showed that the Electronic Frailty Index version we created is valid in predicting mortality or hospitalization. In addition, the Electronic Frailty Index converged with an independent measurement produced by National Social Security.

摘要

背景

衰弱是导致老年人健康和功能恶化的主要因素。

目的

基于 HMO 中常规收集的电子数据开发和验证电子衰弱指数。

研究设计和设置

HMO 成员的回顾性队列。

参与者

120986 名年龄在 2023 年初达到 65 岁及以上的患者。

预测因子

包括 36 项医学、功能和社会缺陷的累积衰弱指数。

结局

一年内全因死亡率或住院率。

统计分析

使用多变量层次 Cox 回归对死亡率或住院的复合结局进行了一年的风险比估计。

结果

EFI 评分的平均值随社会保障护理福利的增加而增加。与健康患者相比,轻度、中度和重度衰弱患者在控制了协变量后,其死亡率或住院的风险分别增加了 2.07 倍、3.35 倍和 4.4 倍。

结论

研究结果表明,我们创建的电子衰弱指数版本在预测死亡率或住院方面是有效的。此外,电子衰弱指数与国家社会保障独立测量结果一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/93c234e034ef/aging-16-206141-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/bdc547a38bad/aging-16-206141-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/a31587762c67/aging-16-206141-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/93c234e034ef/aging-16-206141-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/bdc547a38bad/aging-16-206141-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/a31587762c67/aging-16-206141-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85df/11552639/93c234e034ef/aging-16-206141-g003.jpg

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