Microneedling, also known as collagen induction therapy, is a minimally invasive dermatological procedure that has gained widespread popularity for treating various skin conditions, including acne scars, wrinkles, hyperpigmentation, and stretch marks. By creating controlled micro-injuries in the skin, microneedling stimulates the body's natural healing processes, resulting in increased collagen and elastin production, essential for maintaining skin elasticity and firmness. Over the past few decades, microneedling has evolved significantly, with advancements such as automated devices, radiofrequency microneedling, and combination therapies enhancing its effectiveness and safety profile. This comprehensive review explores the mechanisms of action, various techniques, and clinical applications of microneedling, highlighting its advantages over other skin rejuvenation methods. The review also examines patient satisfaction, safety considerations, and potential complications, providing a balanced perspective on its clinical utility. Furthermore, the discussion includes future directions in microneedling technology and research, focusing on emerging innovations and potential new applications. As the field advances, microneedling is poised to play an increasingly important role in aesthetic medicine, offering a reliable and effective solution for skin rejuvenation and beyond. This review is a valuable resource for healthcare professionals, guiding the optimization of microneedling practices and informing future research efforts.