枯草芽孢杆菌、地衣芽孢杆菌和凝结芽孢杆菌固态发酵产物对肉鸡生长性能及鸡大肠杆菌病的预防作用
Effect of Solid-State Fermentation Products of , , and on Growth Performance of Broilers and Prevention of Avian Colibacillosis.
作者信息
Li Fangfang, Lv Bing, Zuo Jiakun, Nawaz Saqib, Wang Zhihao, Lian Liyan, Yin Huifang, Chen Shuming, Han Xiangan, Wang Haidong
机构信息
College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030801, China.
Shanghai Veterinary Research Institute, The Chinese Academy of Agricultural Sciences (CAAS), 518 Ziyue Road, Shanghai 200241, China.
出版信息
Vet Sci. 2024 Oct 1;11(10):468. doi: 10.3390/vetsci11100468.
This study investigates the impact of the solid-state fermentation products of , , and (LCBs) on the growth characteristics, immune function, intestinal morphology, cecum microbial community, and prevention of avian colibacillosis in broilers. One hundred and twenty Hyland Brown broilers (aged one day) were divided randomly into three groups (four replicates of ten broilers per group). (1) The CON group was fed a basal diet. (2) The MOD group was fed a basal diet. On day 40, APEC strain SX02 (1.1 × 10 CFU/g) was administered to the breasts of chickens in this group. (3) The LCBs group was fed a basal diet supplemented with fermentation products (98.5% basal diet + 0.5% and solid-state fermentation products + 1.0% solid-state fermentation products). On day 40, the LCBs group received the same treatment as the MOD group. The experiment lasted 43 days. This study found that the average daily gain (ADG) of the LCBs group was significantly higher than that of the MOD group ( < 0.05), indicating that LCBs can significantly increase the ADG of broilers and improve the feed conversion ratio. Furthermore, compared to the MOD group, the heart bacterial load was significantly reduced in the LCBs group ( < 0.05), and the lesions less severe in the heart, liver, and jejunum were observed ( < 0.05). Additionally, the detection of intestinal flora showed a significant increase in the abundance of beneficial bacteria in the cecum of the LCBs group, while the number of and decreased significantly. In conclusion, the solid fermentation of , , and can improve the growth performance of broilers while also protecting against avian pathogenic infection. This demonstrates the potential usefulness of these LCBs in feed production.
本研究调查了[具体物质1]、[具体物质2]和[具体物质3](LCBs)的固态发酵产物对肉鸡生长特性、免疫功能、肠道形态、盲肠微生物群落以及预防禽大肠杆菌病的影响。120只海兰褐肉鸡(1日龄)随机分为三组(每组10只肉鸡,共四个重复)。(1)CON组饲喂基础日粮。(2)MOD组饲喂基础日粮。在第40天,向该组鸡的胸部接种APEC菌株SX02(1.1×10 CFU/g)。(3)LCBs组饲喂添加发酵产物的基础日粮(98.5%基础日粮+0.5%[具体物质1]和[具体物质2]固态发酵产物+1.0%[具体物质3]固态发酵产物)。在第40天,LCBs组接受与MOD组相同的处理。实验持续43天。本研究发现,LCBs组的平均日增重(ADG)显著高于MOD组(P<0.05),表明LCBs可显著提高肉鸡的ADG并改善饲料转化率。此外,与MOD组相比,LCBs组心脏细菌载量显著降低(P<0.05),且在心脏、肝脏和空肠中观察到的病变较轻(P<0.05)。另外,肠道菌群检测显示,LCBs组盲肠中有益菌的丰度显著增加,而[有害菌1]和[有害菌2]的数量显著减少。总之,[具体物质1]、[具体物质2]和[具体物质3]的固态发酵可提高肉鸡的生长性能,同时预防禽致病性[病原菌名称]感染。这证明了这些LCBs在饲料生产中的潜在用途。