Suppr超能文献

利用油脂促进皮肤伤口愈合:活性氧调节的作用

Harnessing Oil for Enhanced Skin Wound Healing: The Role of Reactive Oxygen Species Regulation.

作者信息

Israni Dipa K, Raghani Neha R, Soni Jhanvi, Shah Mansi, Prajapati Bhupendra G, Chorawala Mehul R, Mangmool Supachoke, Singh Sudarshan, Chittasupho Chuda

机构信息

Department of Pharmacology, L J Institute of Pharmacy, L J University, Ahmedabad 382210, Gujarat, India.

Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Gandhinagar 382355, Gujarat, India.

出版信息

Pharmaceutics. 2024 Sep 30;16(10):1277. doi: 10.3390/pharmaceutics16101277.

Abstract

emerges as a noteworthy candidate for its medicinal potential, particularly in wound healing. This review article explores the efficacy of cannabis oil in reducing reactive oxygen species (ROS) during the healing of acute and chronic wounds, comparing it to the standard treatments. ROS, produced from various internal and external sources, play a crucial role in wound development by causing cell and tissue damage. Understanding the role of ROS on skin wounds is essential, as they act both as signaling molecules and contributors to oxidative damage. Cannabis oil, recognized for its antioxidant properties, may help mitigate oxidative damage by scavenging ROS and upregulating antioxidative mechanisms, potentially enhancing wound healing. This review emphasizes ongoing research and the future potential of cannabis oil in dermatological treatments, highlighted through clinical studies and patent updates. Despite its promising benefits, optimizing cannabis oil formulations for therapeutic applications remains a challenge, underscoring the need for further research to realize its medicinal capabilities in wounds.

摘要

因其药用潜力,尤其是在伤口愈合方面,成为一个值得关注的候选者。这篇综述文章探讨了大麻油在急性和慢性伤口愈合过程中减少活性氧(ROS)的功效,并将其与标准治疗方法进行比较。ROS由各种内部和外部来源产生,通过导致细胞和组织损伤在伤口发展中起关键作用。了解ROS在皮肤伤口中的作用至关重要,因为它们既作为信号分子又导致氧化损伤。大麻油因其抗氧化特性而闻名,可能通过清除ROS和上调抗氧化机制来帮助减轻氧化损伤,从而潜在地促进伤口愈合。这篇综述强调了大麻油在皮肤病治疗方面的持续研究和未来潜力,通过临床研究和专利更新得以突出体现。尽管有其可观的益处,但优化大麻油用于治疗应用的配方仍然是一个挑战,这凸显了进一步研究以实现其在伤口治疗中的药用能力的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d0c/11510192/a7f440db786b/pharmaceutics-16-01277-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验