Department of Family Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Department of Family Medicine, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
Medicina (Kaunas). 2024 Sep 28;60(10):1596. doi: 10.3390/medicina60101596.
: This study aimed to investigate the association between insulin resistance, as measured by the triglyceride-glucose index (TyG index), and hearing impairment in middle-aged women in Korea. : This cross-sectional survey utilized data from the Korea National Health and Nutrition Examination Survey (KNHANES) IV (2007-2009), specifically from the period after July 21, 2009, when hearing test results became available, and from the KNHANES V (2010-2012). This study was conducted on 5416 women aged 40 to 69 who had completed both the health examination survey and audiometric tests, excluding those with missing data on menopausal status and the use of hormone replacement therapy. : In the study group, the prevalence of high-frequency hearing loss according to the TyG index was significantly higher in the mild hearing loss group (OR = 1.29; 95% CI: 1.12, 1.49, < 0.001) and the moderate hearing loss group (OR = 1.27; 95% CI: 1.09, 1.48, = 0.002). Conversely, the prevalence of low-frequency hearing loss did not show a significant difference in either the mild hearing loss group (OR = 1.17; 95% CI: 0.99, 1.37, = 0.065) and the moderate hearing loss group (OR = 1.13; 95% CI: 0.94, 1.35, = 0.199) : Since diabetes can induce hearing impairment in women, it is recommended that women with a high TyG index undergo early hearing tests.
: 本研究旨在探讨韩国中年女性中,通过三酰甘油-葡萄糖指数(TyG 指数)衡量的胰岛素抵抗与听力损伤之间的关联。: 这项横断面调查利用了韩国国家健康和营养检查调查(KNHANES)IV(2007-2009 年)的数据,具体来说,是在 2009 年 7 月 21 日后可获得听力测试结果的时期,以及 KNHANES V(2010-2012 年)的数据。这项研究纳入了 5416 名年龄在 40 至 69 岁之间、完成了健康检查调查和听力测试的女性,排除了绝经状态和激素替代疗法使用方面数据缺失的女性。: 在研究组中,根据 TyG 指数,高频听力损失的轻度听力损失组(OR=1.29;95%CI:1.12,1.49,<0.001)和中度听力损失组(OR=1.27;95%CI:1.09,1.48,=0.002)的发生率显著更高。相反,低频听力损失的发生率在轻度听力损失组(OR=1.17;95%CI:0.99,1.37,=0.065)和中度听力损失组(OR=1.13;95%CI:0.94,1.35,=0.199)中均无显著差异。: 由于糖尿病可能导致女性听力受损,建议 TyG 指数较高的女性进行早期听力测试。