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采用惠普尔手术成功治疗胰腺成熟性囊性畸胎瘤:一例报告。

Successful management of a pancreatic mature cystic teratoma with Whipple procedure: A case report.

作者信息

Al Jada Iyad, Jabareen Maaweya, Alhroub Wasef, Oweidat Majd

机构信息

Department of Surgery, Hebron University, Hebron, Palestine.

Faculty of Medicine, Hebron University, Hebron, Palestine.

出版信息

Int J Surg Case Rep. 2024 Dec;125:110504. doi: 10.1016/j.ijscr.2024.110504. Epub 2024 Oct 23.

DOI:10.1016/j.ijscr.2024.110504
PMID:39461133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11541951/
Abstract

BACKGROUND

Mature cystic teratomas of the pancreas, also known as dermoid cysts, are exceptionally rare tumors characterized by well-differentiated parenchymal tissues. Typically containing diverse tissues from all three germ layers, these teratomas are most commonly found in the ovaries and testes, with infrequent occurrences in the pancreas.

CASE PRESENTATION

A 30-year-old male with type 2 diabetes mellitus presented with elevated liver enzymes and serum CEA levels. A CT scan detected an 8.8 × 7.2 cm retroperitoneal mass with calcifications. Due to the tumor's involvement with critical structures, a Whipple procedure was performed. Post-surgery, the tumor was confirmed to be a mature cystic teratoma, and the patient experienced a smooth recovery.

DISCUSSION

Pancreatic teratomas are rare, typically affecting younger patients and predominantly occurring in the body or head of the pancreas. These tumors, often categorized into mature and immature types. Diagnosis relies on imaging techniques such as ultrasound, CT, and MRI, which reveal key features like fat, calcifications, and fat-fluid levels. Differential diagnoses include various pancreatic cystic lesions. Surgical resection is the primary treatment, and this case highlights the diagnostic challenges and the critical role of imaging in guiding surgical decisions.

CONCLUSION

This report describes a rare case of a pancreatic mature cystic teratoma, one of only 52 documented cases. Despite the absence of significant symptoms, imaging revealed a large mass, and Whipple procedure was performed due to its complex relationship with vital structures. This case illustrates the diagnostic and therapeutic challenges associated with such rare tumors.

摘要

背景

胰腺成熟囊性畸胎瘤,也称为皮样囊肿,是极为罕见的肿瘤,其特征为实质组织分化良好。这些畸胎瘤通常包含来自所有三个胚层的不同组织,最常见于卵巢和睾丸,在胰腺中很少见。

病例介绍

一名30岁的2型糖尿病男性患者出现肝酶和血清癌胚抗原水平升高。CT扫描发现一个8.8×7.2cm的腹膜后肿块伴有钙化。由于肿瘤累及关键结构,遂进行了惠普尔手术。术后,肿瘤被确诊为成熟囊性畸胎瘤,患者恢复顺利。

讨论

胰腺畸胎瘤罕见,通常影响年轻患者,主要发生在胰腺体部或头部。这些肿瘤常分为成熟型和未成熟型。诊断依赖于超声、CT和MRI等成像技术,这些技术可显示脂肪、钙化和脂液平面等关键特征。鉴别诊断包括各种胰腺囊性病变。手术切除是主要治疗方法,本病例突出了诊断挑战以及成像在指导手术决策中的关键作用。

结论

本报告描述了一例罕见的胰腺成熟囊性畸胎瘤病例,是仅有的52例有记录的病例之一。尽管没有明显症状,但成像显示有一个大肿块,由于其与重要结构的复杂关系,进行了惠普尔手术。本病例说明了与此类罕见肿瘤相关的诊断和治疗挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af7e/11541951/053d80d688f4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af7e/11541951/053d80d688f4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af7e/11541951/053d80d688f4/gr3.jpg

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The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
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Giant teratoma of the pancreas expanding to the mediastinum: Rare tumor and literature review.
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Rare Tumors. 2022 Dec 26;14:20363613221147470. doi: 10.1177/20363613221147470. eCollection 2022.
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Diagnosis and differentiation of mature cystic teratoma of pancreas from its mimics: A case report.胰腺成熟囊性畸胎瘤与其模仿物的诊断与鉴别:一例报告
Medicine (Baltimore). 2020 Nov 20;99(47):e23267. doi: 10.1097/MD.0000000000023267.
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Mature cystic teratoma of the pancreas with 30 years of clinical course: A case report.胰腺成熟囊性畸胎瘤伴30年临床病程:一例报告
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