Chen Shixiong, Liang Ying, Tian Xiaobao, Wang Kai
MOE Key Laboratory of Deep Earth Science and Engineering, College of Architecture & Environment, Sichuan University, Chengdu 610065, P. R. China.
School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Oct 25;41(5):1046-1052. doi: 10.7507/1001-5515.202407099.
The issue of bacterial drug resistance has remained unresolved, and in recent years, biomimetic nanostructured surfaces inspired by nature have garnered significant attention due to their bactericidal properties demonstrated through mechanical mechanisms. This article reviewed the main research progress in the field of nanostructured mechanical bactericidal surfaces, including various preparation methods for nanostructured surfaces with mechanical bactericidal properties, as well as the basic mechanisms and related physical models of the interaction between bacteria and nanostructured surfaces. In addition, the application of nanostructured surfaces in biomedicine was introduced. Finally, the article proposed the major challenges faced by mechanical bactericidal research and the future development direction.
细菌耐药性问题一直未得到解决，近年来，受自然启发的仿生纳米结构表面因其通过机械机制展现出的杀菌特性而备受关注。本文综述了纳米结构机械杀菌表面领域的主要研究进展，包括具有机械杀菌性能的纳米结构表面的各种制备方法，以及细菌与纳米结构表面相互作用的基本机制和相关物理模型。此外，还介绍了纳米结构表面在生物医学中的应用。最后，本文提出了机械杀菌研究面临的主要挑战和未来发展方向。
