Sundt T M, Ebersold M J, Sharbrough F W, Piepgras D G, Marsh W R, Messick J M
Ann Surg. 1986 Feb;203(2):196-204. doi: 10.1097/00000658-198602000-00014.
The relative risk of shunting versus not shunting during carotid endarterectomy was analyzed retrospectively in 1935 cases undergoing carotid endarterectomy for carotid ulcerative stenosis. The need for shunting was based on a correlation between electroencephalographic changes and a fall in cerebral blood flow below the critical level required for adequate perfusion during the period of carotid occlusion. Patients were divided into four risk categories for surgery, based on medical and neurological risks and angiographic findings. Shunts were required in 30% of the low risk group and 56% of the high risk group. Based on the severity of reductions of cerebral blood flow during the period of carotid occlusion it is concluded that 12% of all patients would have sustained a major deficit, 15% a minor or transient deficit, and 20% a transient deficit without shunting. The risk of shunting 792 cases in this series was 0.5%. Overall minor morbidity, major morbidity, and mortality each approximated 1% in this series.
对1935例行颈动脉内膜切除术治疗颈动脉溃疡性狭窄的病例进行回顾性分析,以探讨颈动脉内膜切除术期间分流与不分流的相对风险。是否需要分流是基于脑电图变化与颈动脉闭塞期间脑血流量降至充足灌注所需临界水平以下之间的相关性。根据医疗和神经学风险以及血管造影结果,将患者分为四个手术风险类别。低风险组中30%的患者需要分流,高风险组中56%的患者需要分流。根据颈动脉闭塞期间脑血流量减少的严重程度得出结论,所有患者中12%会出现严重缺损,15%会出现轻度或短暂缺损,20%在不分流的情况下会出现短暂缺损。本系列中792例患者分流的风险为0.5%。本系列中总体轻度发病率、重度发病率和死亡率均约为1%。