Suppr超能文献

一例免疫功能正常患者患脑膜炎的罕见病例:短期抗生素治疗取得成功结果

A Rare Case of Meningitis in an Immunocompetent Patient: A Successful Outcome with a Short Course of Antibiotics.

作者信息

van der Hoeven Adrienne Elisabeth, Kerremans Josephus Johannes, Lagrand Tjerk Joppe

机构信息

Department of Neurology, Alrijne Ziekenhuis, Leiderdorp, The Netherlands.

Department of Medical Microbiology, Alrijne Ziekenhuis, Leiderdorp, The Netherlands.

出版信息

Case Rep Neurol. 2024 Oct 4;16(1):269-273. doi: 10.1159/000541631. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

is a Gram-negative bacterium found in the oral flora of dogs and cats, transmitted to humans through bites, licks, or scratches. Infections can lead to severe manifestations, including meningitis, particularly in immunocompromised individuals.

CASE PRESENTATION

A 46-year-old immunocompetent man presented with somnolence, headache, and fever after being licked by his dog. Neurological examination revealed signs of meningeal irritation, and cerebrospinal fluid analysis showed an elevated white cell count and protein levels consistent with bacterial meningitis. Treatment followed Dutch guidelines with amoxicillin, ceftriaxone, and dexamethasone, resulting in rapid clinical improvement. Microbiological confirmation of . followed later. The patient was treated with antibiotics for the duration of 1 week and remained symptom-free after being discharged.

CONCLUSION

meningitis, although rare, poses diagnostic challenges due to its variable presentation and slow growth in culture. Empirical therapy guided by susceptibility testing contributes to favorable outcomes. This case underscores the importance of considering a . infection in patients with animal exposure and of taking diagnostic findings, precedent, and clinical response into account when determining the treatment duration.

摘要

引言

是一种革兰氏阴性菌,存在于犬猫口腔菌群中,可通过咬伤、舔舐或抓挠传播给人类。感染可导致严重表现,包括脑膜炎,尤其是在免疫功能低下的个体中。

病例介绍

一名46岁免疫功能正常的男性在被其狗舔舐后出现嗜睡、头痛和发热症状。神经系统检查发现脑膜刺激征,脑脊液分析显示白细胞计数和蛋白质水平升高,符合细菌性脑膜炎表现。治疗遵循荷兰指南,使用阿莫西林、头孢曲松和地塞米松,临床症状迅速改善。随后进行了 的微生物学确诊。患者接受了为期1周的抗生素治疗,出院后无症状。

结论

脑膜炎虽然罕见,但因其表现多样且在培养中生长缓慢,给诊断带来挑战。药敏试验指导下的经验性治疗有助于取得良好疗效。本病例强调了在有动物接触史的患者中考虑 感染的重要性,以及在确定治疗疗程时考虑诊断结果、先例和临床反应的重要性。

相似文献

本文引用的文献

5
Corticosteroids for acute bacterial meningitis.用于急性细菌性脑膜炎的皮质类固醇
Cochrane Database Syst Rev. 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5.
7
Capnocytophaga canimorsus.卡他莫拉菌。
Vet Microbiol. 2010 Jan 27;140(3-4):339-46. doi: 10.1016/j.vetmic.2009.01.040. Epub 2009 Feb 5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验