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免疫功能正常个体中无犬咬伤的嗜二氧化碳噬纤维菌脑膜炎和菌血症。

Capnocytophaga canimorsus meningitis and bacteraemia without a dog bite in an immunocompetent individual.

机构信息

General Medicine, Mercy University Hospital, Cork, Ireland

Microbiology, Mercy University Hospital, Cork, Ireland.

出版信息

BMJ Case Rep. 2021 Jul 21;14(7):e242432. doi: 10.1136/bcr-2021-242432.

Abstract

We describe the case of an immunocompetent 75-year-old man with bacteraemia and meningitis. commonly found in the oral flora of dogs with human infection typically occurring following a bite. Unusually, while our patient was a dog owner, there was no history of bite nor scratch mark. Admission blood cultures flagged positive for Gram-negative bacilli, but prolonged molecular analysis was required before was isolated in blood and cerebrospinal fluid. There is a high mortality rate in invasive infection, and in our patient's case, antibiotic therapy was commenced prior to laboratory confirmation with our patient making a complete recovery. This case highlights the importance of including in the differential diagnosis of unwell patients who keep dogs, even without a bite. This case occurred amid heightened awareness of COVID-19, which may represent predisposition for zoonoses during social isolation and increased human-pet contact.

摘要

我们描述了一例免疫功能正常的 75 岁男性,他患有菌血症和脑膜炎。通常在狗的口腔菌群中发现,人类感染通常发生在被咬伤之后。不同寻常的是,尽管我们的患者是狗的主人,但他没有被咬伤或抓伤的病史。入院血培养 flagged 出革兰氏阴性杆菌呈阳性,但在血液和脑脊液中分离出 之前,需要进行长时间的分子分析。侵袭性感染的死亡率很高,在我们的患者病例中,在实验室确认之前就开始了抗生素治疗,患者完全康复。 即使没有被咬伤,该病例也强调了在不舒适的养狗患者的鉴别诊断中包括 的重要性。在 COVID-19 意识增强的情况下发生了这种情况,这可能代表社交隔离和人与宠物接触增加期间导致人畜共患病的易感性。

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