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光学与光声成像:机遇与挑战

Optical and Photoacoustic Imaging : Opportunities and Challenges.

作者信息

Zhang Xuan, Wu Ying, Chen Lanlan, Song Jibin, Yang Huanghao

机构信息

MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou 350108, China.

State Key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, China.

出版信息

Chem Biomed Imaging. 2023 Mar 20;1(2):99-109. doi: 10.1021/cbmi.3c00009. eCollection 2023 May 22.

Abstract

Optical and photoacoustic imaging plays an important role in biomedical applications owing to its noninvasiveness and high resolution. Fluorescence imaging and photoacoustic imaging emerge as powerful tools to deconstruct molecular information and investigate biological processes . Despite great progress has been achieved in chemical probe synthesis, how to design probes with optimal fluorescence or photoacoustic imaging performance to dynamically visualize the biological process still faces challenges. From this perspective, we will focus on the advanced development of fluorescence and photoacoustic imaging . Furthermore, concerns and prospects for future imaging will be demonstrated.

摘要

光学成像和光声成像因其非侵入性和高分辨率在生物医学应用中发挥着重要作用。荧光成像和光声成像成为解构分子信息和研究生物过程的强大工具。尽管在化学探针合成方面取得了巨大进展,但如何设计具有最佳荧光或光声成像性能的探针以动态可视化生物过程仍面临挑战。从这个角度来看,我们将专注于荧光成像和光声成像的前沿发展。此外,还将阐述对未来成像的关注和展望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1e2/11504558/7a43f8902b88/im3c00009_0001.jpg

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