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Tumor derived cell-free nucleic acid upregulates programmed death-ligand 1 expression in neutrophil via intracellular Toll-like receptor signaling.

作者信息

Saito Suguru, Cao Duo-Yao, Shibata Tomohiro, Liu Yan, Otagiri-Hoshi Aoi, Cui Xiaojiang, Bernstein Kenneth E

机构信息

Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Department of Pharmacology, School of Medicine, Yokohama City Univeristy, Yokohama, Kanagawa, Japan.

出版信息

Cancer Commun (Lond). 2025 Jan;45(1):4-8. doi: 10.1002/cac2.12615. Epub 2024 Oct 30.

DOI:10.1002/cac2.12615
PMID:39474920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11758147/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0403/11758147/a0199d4c2552/CAC2-45-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0403/11758147/a0199d4c2552/CAC2-45-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0403/11758147/a0199d4c2552/CAC2-45-4-g001.jpg

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Tumor-Infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis.GM-CSF诱导的肿瘤浸润性PD-L1+中性粒细胞抑制喉鳞状细胞癌中的T细胞功能并预示不良预后。
J Inflamm Res. 2022 Feb 16;15:1079-1097. doi: 10.2147/JIR.S347777. eCollection 2022.
3
Cell-free DNA analysis in current cancer clinical trials: a review.
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