Miyamoto Hizuru, Tahara Kentarou, Hirano Eiichi
Dentistry and Oral Surgery of Happy Town, Shiki, Saitama, Japan.
Medical Affairs Department, Japan Bio Products, Co., Ltd., Shibuya, Tokyo, Japan.
Int Med Case Rep J. 2024 Oct 26;17:883-890. doi: 10.2147/IMCRJ.S487611. eCollection 2024.
The placenta extract is used as a dietary supplement. We aimed to investigate the effects of placenta extract on periodontal disease.
In this study, placenta extract supplements were found to improve the oral environment of young and middle-aged Japanese women undergoing maintenance; after three months of taking placenta extract, bleeding upon probing was reduced. In addition, two parameters, white blood cells and protein, improved in the SillHa test, suggesting that the placenta extract contributes to the reduction of gingival inflammation through its anti-inflammatory effect. No adverse events were observed with the placenta extract.
Placenta extract may lead to better management, including oral rehabilitation and pharmacotherapy. However, its effect on gingival inflammation requires further investigation in a larger number of cases.
胎盘提取物被用作膳食补充剂。我们旨在研究胎盘提取物对牙周疾病的影响。
在本研究中，发现胎盘提取物补充剂可改善接受维护治疗的日本中青年女性的口腔环境；服用胎盘提取物三个月后，探诊出血减少。此外，在希尔哈试验中，白细胞和蛋白质这两个参数有所改善，表明胎盘提取物通过其抗炎作用有助于减轻牙龈炎症。未观察到胎盘提取物有不良事件。
胎盘提取物可能有助于包括口腔修复和药物治疗在内的更好管理。然而，其对牙龈炎症的影响需要在更多病例中进一步研究。
