Cohen M M, Duncan P G, Pope W D, Wolkenstein C
Can Anaesth Soc J. 1986 Jan;33(1):22-31. doi: 10.1007/BF03010904.
This paper describes the outcome of a nine-year post-anaesthetic followup program in a large teaching hospital (N = 112,721 anaesthetics). Between time periods 1975-78 and 1979-83, more seriously ill patients (higher ASA physical status) were being treated. Anaesthetic practice also changed, with an increased use of balanced (multiple drug) anaesthetic procedures, a decrease in the use of halothane and an increase in the use of monitoring. Nonfatal anaesthetic complications--intraoperative, recovery room and postoperative--were rare but there was an increase in the reported complication rate over time. From 1975-78, 7.6 per cent of all cases had at least one intraoperative complication and from 1979-83, this rose to 10.6 per cent of all cases. For recovery room complications, there was an increase to 5.9 per cent in 1979-83 from 3.1 per cent in 1975-78. In time period 2 there was a 9.4 per cent chance of having a postoperative anaesthetic-related complication, and a 0.45 per cent chance of a significant morbidity as a result. This represents an increase over time period 1 (8.9 and 0.40 per cent respectively). It is concluded that the anaesthetic experience, while associated with low mortality rates in recent years, is still associated with significant morbidity. It is conjectural at present whether this is reflective of preoperative patient status, anaesthetic practice, or other undefined variables associated with an operative experience.
本文描述了一家大型教学医院开展的一项为期九年的麻醉后随访项目的结果(共112,721例麻醉病例)。在1975 - 1978年和1979 - 1983年这两个时间段内,接受治疗的病情较重的患者(ASA身体状况分级较高)增多。麻醉实践也发生了变化,平衡(多种药物)麻醉程序的使用增加,氟烷的使用减少,监测的使用增加。非致命性麻醉并发症——术中、恢复室及术后的并发症——较为罕见,但报告的并发症发生率随时间有所增加。1975 - 1978年,所有病例中有7.6%至少发生了1例术中并发症,1979 - 1983年,这一比例升至所有病例的10.6%。恢复室并发症方面,发生率从1975 - 1978年的3.1%增至1979 - 1983年的5.9%。在第二个时间段,术后发生与麻醉相关并发症的概率为9.4%,由此导致严重发病的概率为0.45%。这相较于第一个时间段(分别为8.9%和0.40%)有所增加。得出的结论是,近年来麻醉经验虽与低死亡率相关,但仍与显著的发病率相关。目前尚不确定这是反映了术前患者状况、麻醉实践,还是与手术经历相关的其他未明确的变量。