埃塞俄比亚亚的斯亚贝巴某选定公立医院成年乳腺癌患者的抑郁状况及相关因素

Depression and associated factors among adult breast cancer patients attending at selected public hospital in Addis Ababa, Ethiopia.

作者信息

Sebro Etalemahu, Biranu Endalkchew, Nigussie Altaye, Gebremedhin Tadesse, Sisay Million Molla, Shaweno Tamrat

机构信息

Department of Epidemiology, Jimma University Institute of Health, Jimma, Ethiopia.

St. Peter's Specialized Hospital, Research and Evidence Generation Directorate, Addis Ababa, Ethiopia.

出版信息

SAGE Open Med. 2024 Oct 16;12:20503121241283727. doi: 10.1177/20503121241283727. eCollection 2024.

DOI:10.1177/20503121241283727

PMID:39483618

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11526312/

Abstract

BACKGROUND

Depression is a major public health problem among adult breast cancer patients. Although there are few studies on depression, data were mainly from a single center and the potential risk factors were not exhaustively addressed. Thus, we aimed to investigate the prevalence of depression and risk factors among adult breast cancer patients at two big hospitals in Addis Ababa.

OBJECTIVE

To assess depression and its associated factors among breast cancer patients attending public hospitals in Addis Ababa, Ethiopia, in 2021.

METHODS

An institution-based cross-sectional study was conducted among adult patients with breast cancer attending at Tikur Anbessa Specialized Hospital and St. Paul's Hospital Millennium Medical College from June to July 2021. Simple random sampling was used to obtain a sample size of 318. Data were collected using the standard Patient Health Questionnaire-9, structured questionnaire interviews, and chart reviews. SPSS version 25 was used for analysis; the correlation between independent and dependent variables was evaluated using a logistic regression model. Each analysis regarded a -value less than 0.05 as statistically significant.

RESULT

The mean age of the participants was 43.1 ± 11.3 years. The prevalence of depression among adult breast cancer patients was 33 (10.6%), and according to the patient health questionnaires (PHQ)-9 score categorization, 116 (37.3%) were minor, 28 (9%) were moderate, and 5 (1.6%) had moderate severity. The duration of diagnosis was <12 months and stage 2 breast cancer was more protective against depression than stage 4 breast cancer. A lower monthly income and poor social support were significantly associated with depression.

CONCLUSION

The prevalence of depression was moderate among adult patients with breast cancer; the stage of cancer, duration of diagnosis, income, and poor social support were significantly associated with depression, emphasizing the value of counseling.

摘要

背景

抑郁症是成年乳腺癌患者中的一个主要公共卫生问题。尽管关于抑郁症的研究较少，且数据主要来自单一中心，潜在风险因素也未得到详尽探讨。因此，我们旨在调查亚的斯亚贝巴两家大型医院成年乳腺癌患者中抑郁症的患病率及风险因素。

目的

评估2021年埃塞俄比亚亚的斯亚贝巴公立医院乳腺癌患者中的抑郁症及其相关因素。

方法

2021年6月至7月，在提库尔·安贝萨专科医院和圣保罗医院千年医学院对成年乳腺癌患者进行了一项基于机构的横断面研究。采用简单随机抽样获得318名样本量。通过标准的患者健康问卷-9、结构化问卷访谈和病历审查收集数据。使用SPSS 25版进行分析；使用逻辑回归模型评估自变量和因变量之间的相关性。每次分析将P值小于0.05视为具有统计学意义。

结果

参与者的平均年龄为43.1±11.3岁。成年乳腺癌患者中抑郁症的患病率为33例（10.6%），根据患者健康问卷（PHQ）-9评分分类，116例（37.3%）为轻度，28例（9%）为中度，5例（1.6%）为重度。诊断时间<12个月，2期乳腺癌比4期乳腺癌对抑郁症的防护作用更强。月收入较低和社会支持较差与抑郁症显著相关。